Sökning: "hypoxic pulmonary vasoconstriction"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden hypoxic pulmonary vasoconstriction.

  1. 1. Hypoxic pulmonary vasoconstriction and nitric oxide

    Författare :Kristina Hambraeus Jonzon; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :hypoxia; pulmonary vasoconstriction; regional pulmonary bloodflow; stimulus-response; nitric oxide; blood-borne distant effects; nitric oxide synthase activity; inhaled; exhaled; non-enzymatic;

    Sammanfattning : Hypoxia causes pulmonary vasoconstriction (HPV), improving oxygenation by redistribution of the pulmonary blood flow to better oxygenated lung regions. HPV is intrinsic to the pulmonary vascular smooth muscle cell, but can be modulated by several vasoactive substances, as for example endothelium derived nitric oxide (NO) and endothelin-1 (ET-1). LÄS MER

  3. 2. Endothelin in the pulmonary circulation with special reference to hypoxic pulmonary vasoconstriction

    Författare :Peter Holm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :bosentan; BMS-182874; ; BQ-123; BQ-788; endothelin; endothelium; hypoxia; hypoxic pulmonary vasoconstriction; pulmonary hypertension; receptor antagonism; TBC 11251.;

    Sammanfattning : A number of substances originating from the pulmonary endothelium have recently been found to be involved in the regulation of pulmonary vascular tone. Accumulating evidence suggests that endothelial dysfunction contributes to pulmonary hypertension, an important clinical problem often associated with hypoxemia. LÄS MER

  4. 3. Pulmonary hypertension related to heart failure and hypoxia. Mechanisms, new treatment strategies and impact on mortality following heart transplantation. Experiences from Skåne University Hospital in Lund

    Författare :Jakob Lundgren; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pulmonary hypertension; Left heart disease; Heart Transplantation; ADMA; Survival; Hemodynamics; Soluble guanylate cyclase; Endothelin receptor antagonist; L-Arginine; Hypoxic pulmonary vasoconstriction;

    Sammanfattning : .... LÄS MER

  5. 4. Modulators of hypoxic pulmonary vasoconstriction and pulmonary hypertension. Implications for new treatment strategies

    Författare :DAVID KYLHAMMAR; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : .... LÄS MER

  7. 5. Benefits of Spontaneous Breathing : Compared with Mechanical Ventilation

    Författare :László Vimláti; Michael Lichtwarck-Aschoff; Anders Larsson; Lars Wiklund; Carl-Johan Wickerts; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; spontaneous breathing; mechanical ventilation; pulmonary shunt; oxygenation; hypoxic pulmonary vasoconstriction; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Sammanfattning : When spontaneous breathing (SB) is allowed during mechanical ventilation (MV), atelectatic lung areas are recruited and oxygenation improves thereby. Whether unsupported SB at its natural pattern (without PEEP and at low pressure/small tidal volume) equally recruits and improves oxygenation, and if so by which mechanism, has not been studied. LÄS MER