Sökning: "Christian Hackenberger"

Hittade 2 avhandlingar innehållade orden Christian Hackenberger.

  1. 1. Synthesis and investigation of bacterial effector molecules

    Författare :Michael Franz Albers; Christian Hedberg; Christian Hackenberger; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bacterial effectors; organic synthesis; Legionella; PTM; peptide synthesis; nucleotide chemistry; Biorganic Chemistry; bioorganisk kemi;

    Sammanfattning : During infections, bacterial microorganisms initiate profound interactions with mammalian host cells. Usually defense mechanisms of the host destroy intruding bacteria in rapid manner. However, many bacterial pathogens have evolved in a way to avoid these mechanisms. LÄS MER

  3. 2. Site-specific labeling of affinity molecules for in vitro and in vivo studies

    Författare :Anna Perols; Amelie Eriksson Karlström; Christian Hackenberger; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Affibody molecules; molecular imaging; site-specific labeling; solid phase peptide synthesis; IgG-binding domains; photoconjugation.; Bioteknologi; Biotechnology;

    Sammanfattning : The thesis is focused on site-specific labeling of affinity molecules for different applications where two types of binding proteins, Affibody molecules and antibodies, have been used. For the purpose of improving the properties of Affibody molecules for in vivo imaging, novel bi-functional chelators for radiolabeling using the radionuclide 111In were evaluated. LÄS MER