Sökning: "neutropenia"

Visar resultat 11 - 15 av 37 avhandlingar innehållade ordet neutropenia.

  1. 11. Pharmacometric Evaluation of Biomarkers to Improve Treatment in Oncology

    Författare :Ida Netterberg; Lena Friberg; Mats Karlsson; Elisabet I. Nielsen; Henrik Lindman; Amit Roy; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometrics; Biomarkers; Oncology; Population PKPD Modeling; NONMEM; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Cancer is a family of many different diseases with substantial heterogeneity also within the same cancer type. In the era of personalized medicine, it is desirable to identify an early response to treatment (i.e., a biomarker) that can predict the long-term outcome with respect to both safety and efficacy. LÄS MER

  3. 12. Severe viral respiratory tract infections in children

    Författare :Samuel Arthur Rhedin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Respiratory tract infections (RTIs) are estimated to cause 703.000 deaths annually in children below five years. The majority of RTIs in children are caused by viruses, yet the number of antivirals approved for treatment of these infections is very limited. LÄS MER

  4. 13. Improving chemotherapy in advanced urothelial cancer : real-world data studies and prospective clinical trials

    Författare :Karin Holmsten; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Advanced urothelial cancer (UC) is an aggressive disease with high morbidity and mortality. The primary aim of this thesis was to improve chemotherapy with respect to treatment efficacy, safety, and health-related quality of life (HRQoL) in advanced UC. LÄS MER

  5. 14. Toxicity and pharmacokinetic biomarkers for personalized non-small cell lung cancer treatment

    Författare :Anna Svedberg; Henrik Green; Svante Vikingsson; Joakim Lundeberg; Mikko Niemi; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Lung cancer is the leading cause of cancer-related deaths worldwide. Unfortunately, lung cancer is usually discovered at a late stage when the curative treatment options are limited. The treatment can include surgery, radiation, chemotherapy, targeted therapy and now also immunotherapy. LÄS MER

  7. 15. Understanding cellular and cytoskeletal dysregulation in immunodeficiency diseases

    Författare :Anton Sendel; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The immune system is a complex network of cells and molecules interacting to preserve the integrity and survival of the host by distinguishing self from non-self, and dysregulation of immune cells can lead to immunodeficiency, autoimmunity, and cancer. The cytoskeleton is essential for several important immune cell functions, including proliferation, movement, signaling, and vesicle trafficking. LÄS MER