Sökning: "mitoribosome small subunit"

Hittade 5 avhandlingar innehållade orden mitoribosome small subunit.

  1. 1. Characterization of land plant-specific proteins required for mitochondrial translation initiation

    Författare :Huy Cuong Tran; Molekylär cellbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mitochondrial unfolded protein response; Arabidopsis mitochondrial isolation; mitoribosome; mitochondrial translation initiation; mitoribosome small subunit; mTRAN; mTRAN-mRNA interaction;

    Sammanfattning : Plant mitochondria produce the majority of adenosine triphosphate (ATP) – the cellular energy currency for metabolic reactions needed for plant growth, development, and maintenance. Despite a relatively thorough understanding of basic mitochondrial functions, many mitochondrial proteins and processes remain poorly understood. LÄS MER

  3. 2. Structural investigation of human mitochondrial translation and off-target antibiotic binding

    Författare :Vivek Singh; Alexey Amunts; Yaser Hashem; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mitochondrial translation; mitoribosome; electron cryo-microscopy; LRPPRC-SLIRP; antibiotics; streptomycin; Biophysics; biofysik;

    Sammanfattning : Human mitochondrial translation machinery has evolved to translate 13 mitochondrial mRNAs encoding components of the oxidative phosphorylation pathway responsible for ATP production. The structural basis of human mitochondrial translation is distinct from the canonical bacterial and cytosolic translation systems. LÄS MER

  4. 3. The mitoribosome as a hub for integrating mitochondrial gene expression : Regulation of translation and early assembly of cytochrome b

    Författare :Andreas Carlström; Martin Ott; Chris Meisinger; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mitochondria; gene expression; mitochondrial ribosome; translation regulation; feedback loop; biokemi; Biochemistry;

    Sammanfattning : The mitochondrial proteome is a mosaic of proteins from two different genetic systems. The majority of mitochondrial proteins are encoded in the nuclear genome and are synthesized in the cytosol before imported to mitochondria. LÄS MER

  5. 4. The interactome of the yeast mitochondrial ribosome : Organization of mitochondrial post-transcriptional regulation, membrane protein insertion and quality control

    Författare :Braulio Vargas Möller-Hergt; Martin Ott; Michal Minczuk; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; mitochondrial post-transcriptional regulation; mitochondrial ribosome; membrane protein insertion; mitochondrial quality control; Biochemistry; biokemi;

    Sammanfattning : The proteins found in mitochondria originate from two different genetic systems. Most mitochondrial proteins are synthesized in the cytosol and post-translationally imported into the organelle. However, a small subset of mitochondrial proteins is encoded in an organelle-resident genome. LÄS MER

  7. 5. Role of mitochondrial ribosomal protein S18-2 in cancerogenesis and in regulation of stemness and differentiation

    Författare :Muhammad Mushtaq; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mitochondria carry their own ribosomes (mitoribosomes) for the translation of mRNA encoded by mitochondrial DNA. The architecture of mitoribosomes is mainly composed of mitochondrial ribosomal proteins (MRPs), which are encoded by nuclear genomic DNA. LÄS MER