Sökning: "matrix stratification"

Visar resultat 6 - 10 av 14 avhandlingar innehållade orden matrix stratification.

  1. 6. Studies of anemia in the myelodysplastic syndromes

    Författare :Martin Jädersten; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Myelodysplasia; growth factors; Cox regression; delayed entry; left truncation; mortality; international prognostic scoring system; IPSS; who-classification based prognostic scoring system; WPSS; thalidomide analogue; IMiD; hematopoietic stem cell; adhesion; stroma; matrix; osteonectin; matricellular protein; NPM1; immunohistochemistry.;

    Sammanfattning : Background: The myelodysplastic syndromes (MDS) constitute a heterogeneous group of malignant bone marrow disorders, characterized by chronic anemia and increased risk of transformation to acute myeloid leukemia (AML). The first line therapy of anemia in MDS is erythropoietin (EPO) with or without granulocyte colony-stimulating factor (G-CSF). LÄS MER

  3. 7. Generation of Leachate and the Flow Regime in Landfills

    Författare :David Bendz; Avdelningen för Teknisk vattenresurslära; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; teknisk geologi; Hydrogeologi; geographical and geological engineering; Hydrogeology; model; transport; flow; leachate; water; hydrology; landfill; MSW; teknisk geografi; Geophysics; physical oceanography; meteorology; Geofysik; fysisk oceanografi; meteorologi;

    Sammanfattning : The environmental impacts of landfills are associated mainly with the emission of leachate and biogas. Sanitary landfilling aims to stabilize the landfill in a efficient and controlled way, so that the environmental impacts are minimized. When a sanitary landfill has attained its final storage quality, it can be integrated into the environment. LÄS MER

  4. 8. Tumour stromal and demographical factors affecting the metastatic aggressiveness of small differentiated papillary thyroid cancers in Sweden

    Författare :Haytham Bayadsi; Joakim Hennings; Malin Sund; Robert Bränström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Papillary thyroid cancer; Tumour stroma; Geographic information system; Register; Surgery; kirurgi;

    Sammanfattning : Background: The incidence of papillary thyroid cancer (PTC) has been increasing over the recent decades, especially that of small papillary thyroid cancers (sPTCs) (≤ 20mm in size). sPTCs are generally classified as low risk cancers with a very favourable diagnosis, yet some of these cancers still cause locoregional and distant metastasis, recurrence and even death. LÄS MER

  5. 9. Improving stroke risk prediction and individualised treatment in carotid atherosclerosis

    Författare :Eva Karlöf; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Unstable carotid atherosclerosis causes stroke, but methods to identify patients and lesions at risk are lacking. Currently, this risk estimation is based on measurements of stenosis and neurological symptoms, which determines the therapy of either medical treatment with or without carotid endarterectomy. LÄS MER

  7. 10. Molecular Epidemiology of Cardiovascular Disease

    Författare :Markus Stenemo; Johan Ärnlöv; Rikard Landberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomarkers; ischemic stroke; heart failure; omics; proteomics; metabolomics; epidemiology; risk marker; Epidemiologi; Epidemiology;

    Sammanfattning : Cardiovascular disease is a major cause of morbidity and mortality, with increasing prevalence worldwide.Identification of risk markers may enable improved prevention by targeting high-risk individuals, earlier disease diagnosis and treatment, as well as stratification of disease subtypes with different treatment options, thereby minimizing side effects while increasing success rates. LÄS MER