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1. 1. Cellular Studies of HER-family Specific Affibody Molecules

   Författare :Lovisa Göstring; Lars Gedda; Jörgen Carlsson; Fredrik Frejd; Håkan Hedman; Uppsala universitet; []
   Nyckelord :EGFR; HER2; HER3; Affibody; internalisation; tumour targeting; MEDICINE; MEDICIN;

   Sammanfattning : The human epidermal growth-factor like receptor (HER) family of receptor tyrosine kinases are important targets for cancer therapy. The family consists of four members - EGFR, HER2, HER3 and HER4 - that normally transfer stimulatory signals from extracellular growth factors to the intracellular signalling network. LÄS MER