Sökning: "liver endothelial cells"

Visar resultat 11 - 15 av 48 avhandlingar innehållade orden liver endothelial cells.

  1. 11. Alcohol and inflammation : a study of effects of ethanol on endothelial and epithelial cell functions

    Författare :Anne-Sofie Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Although short–term alcohol drinking causes euphoric and stress relieving effects, alcohol abuse is a major risk factor for neurobehavioural, liver and muscle injury as well as reduced host defence with enhanced susceptibility to bacterial infections. Although such reductions also suggest potential use as an anti-inflammatory drug, well known side effects of ethanol limits its clinical use. LÄS MER

  3. 12. Interaction between insulin and IGF-I receptors in insulin sensitive and insulin resistant cells and tissues

    Författare :Karolina Bäck; Hans Arnqvist; Hans Tornqvist; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Insulin and insulin-like growth factor I (IGF-I) are two related peptides with similar structure. They mediate their effects by binding to their respective receptor, the insulin receptor (IR) and the IGF-I receptor (IGF-IR) and induce intracellular signalling cascades resulting in metabolic or mitogenic effects. LÄS MER

  4. 13. Human cytomegalovirus and dendritic cell interaction : role in immunosupression and autoimmunity

    Författare :Stefania Varani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cytomegalovirus; myeloid dendritic cells; plasmacytoid dendritic cells; immunosuppression; autoimmunity.;

    Sammanfattning : Human cytomegalovirus (HCMV) infection is a major cause of morbidity and mortality in patients with an impaired immune system. The virus itself can cause transitory but significant immunosuppression in immunocompetent as well as immunocompromised infected individuals. LÄS MER

  5. 14. Modifying xenogeneic immune recognition and engraftment by genetic engineering

    Författare :Zhong He; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Xenotransplantation; gene therapy; gene transfer; endothelium; promoters; monocytes; NK cells; alpha-Gal; lentivirus vectors; pancreatic islets;

    Sammanfattning : Transplantation using xenogenic organs, tissues and cells (i.e. xenotransplantation) is a potential solution to the shortage of those from human sources. Vascular endothelial cells (ECs) are the most immediate barrier between the xenogeneic donor organ and the host defense systems. LÄS MER

  7. 15. Elimination of circulation IgA and IgS immune complexes : An experimental study in mice, rats and guinea pigs

    Författare :Anders Johansson; Ann Kari Lefvert; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Immune complexes were formed between dinitrophenyl- (DNP-) conjugated human serum albumin (HSA) and anti-DNP antibodies (monoclonal mouse IgA or polyclonal rabbit IgG). Blood clearance and tissue distribution of intravenously injected labelled antigen and immunecomplex preparations were studied in mice, rats and guinea pigs. LÄS MER