Sökning: "lipid droplets"

Visar resultat 16 - 20 av 39 avhandlingar innehållade orden lipid droplets.

  1. 16. Characterisation of autophagy pathways in atherosclerosis

    Författare :Peter Saliba Gustafsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atherosclerosis is an inflammatory disease of large to intermediate-sized arteries, characterised by retention of modified low-density lipoprotein within the vessel wall; this evokes an inflammatory response. Low-density lipoprotein carries lipids such as fatty acids, triglycerides and cholesterol, from the liver to peripheral tissues. LÄS MER

  3. 17. Genetic and functional studies of MTTP and PLIN2 in relation to metabolic and cardiac dysfunction

    Författare :Anna Aminoff; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Lipids including triglycerides, cholesterol, cholesterol esters and fatty acids are important sources for energy production, act as building blocks for intracellular compartments, are involved in numerous biological pathways and may act as signal molecules. Lipids are transported in blood as lipoproteins between organs, where they are immediately used in cellular processes or stored as cytosolic lipid droplets. LÄS MER

  4. 18. Identification and functional characterization of proteins involved in hepatic triglyceride metabolism

    Författare :Apostolos Taxiarchis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Triglycerides are the main form of energy in the tissues and liver, along with the adipose tissue, is the main organ of triglyceride metabolism and storage in the lipid-droplet organelles. A number of proteins are involved in the regulation of the triglyceride metabolism in human liver, however their specific role is still not thoroughly known. LÄS MER

  5. 19. Vascular metabolomics : role of VEGF-B in fatty acid uptake and metabolic disease

    Författare :Carolina Hagberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The incidence of type 2 diabetes and the metabolic syndrome is rapidly increasing among both adults and children worldwide. Type 2 diabetes is strongly associated with obesity and ectopic lipid accumulation. Recent research has shown that peripheral insulin sensitivity is directly impaired by excessive lipid deposition within tissues. LÄS MER

  7. 20. Shining Light on Benzothiadiazoles and Indolines : Photophysical Properties and Cancer Cell Imaging

    Författare :Susanne Doloczki; Christine Dyrager; Andrey Klymchenko; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Sammanfattning : Fluorescent molecules, also called fluorophores, play an important role in life sciences. As crucial tools in fluorescence microscopy, they can be used to study biological processes on a cellular level, which is a fundamental aspect of cancer research. LÄS MER