Sökning: "infectious diseases Immunology Tumour immunology"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden infectious diseases Immunology Tumour immunology.

  1. 1. Immunological Checkpoint Blockade and TLR Stimulation for Improved Cancer Therapy

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Sara Mangsbo; Uppsala universitet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CpG ODNs; TLR-9; CTLA-4; PD-1; PD-L1; B7. H1; immunotherapy; checkpoint blockade; bladder cancer; cancer; complement; TLRs; Compstatin; properdin; C3; experimental animal model; whole blood loop system; combination therapies; MEDICINE Microbiology; immunology; infectious diseases Immunology Clinical immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi Klinisk immunologi; MEDICINE Microbiology; immunology; infectious diseases Immunology Tumour immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi Tumörimmunologi; immunologi; Immunology;

    Sammanfattning : This thesis concerns the investigation of novel immunotherapies for cancer eradication. CpG therapy was used in order to target antigen-presenting cells (APCs), facilitating antigen presentation and activation of T cells. LÄS MER

  2. 2. Anti-tumour effect in solid tumours, tolerance and immune reconstition after allogeneic haematopoietic stem cell transplantation

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Immunology, Microbiology, Pathology and Infectious Diseases

    Författare :Patrik Hentschke; Karolinska Institutet.; Karolinska Institutet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Both in haematological malignancies and in disseminated solid tumours, re-occurrence of the underlying disease is the main complication. Allogeneic haematopoietic stem cell transplantation (HSCT) increases the chance of cure compared to only chemotherapy in haematological malignancies, but adds the risk of immunological complications such as graft-versus-host disease (GVHD) and severe infections. LÄS MER

  3. 3. Potential role of anti-cytokine autoantibodies in the regulation of cytokine responses in infections and autoimmune diseases

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Immunology, Microbiology, Pathology and Infectious Diseases

    Författare :Rihab Abdel Magid Awad El Karim; Karolinska Institutet.; Karolinska Institutet.; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytokines; autoantibodies; MS; AM; ST; MGUS; GBS; lower respiratory tract infection; mAbs;

    Sammanfattning : Anti-cytokine autoantibodies are serum proteins that bind cytokines and specifically interfere with measurements and biological activities of the corresponding cytokines. Plasma, sera, and CSF were obtained from patients with multiple sclerosis (MS), aseptic meningitis (AM), stroke (ST), and polyneuropathy, Guillain Barré Syndrome (GBS). LÄS MER

  4. 4. Leukaemic relapse after allogeneic haematopoietic stem cell transplantation and the use of the graft-versus-leukaemia effect

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Immunology, Microbiology, Pathology and Infectious Diseases

    Författare :Stefan Carlens; Karolinska Institutet.; Karolinska Institutet.; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; haematopoietic stem cell transplantation; GVHD; GVL; DLI; T-cell culture; retroviral transduction; NK-cell culture;

    Sammanfattning : Survival after allogeneic haematopoietic stem cell transplantation (HSCT) has improved over the last decades due to improvements in immunosuppressive regimens and supportive care. Today the major risk of treatment failure is recurrent leukaemia, a risk which has stayed relatively constant over the years. LÄS MER

  5. 5. Human papillomaviruses : role in cervical dysplasia and carcinoma, and use as molecular risk marker for progression

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Immunology, Microbiology, Pathology and Infectious Diseases

    Författare :Mina Kalantari; Karolinska Institutet.; Karolinska Institutet.; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human papillomavirus; high risk; HPV; PCR; typing; cervical carcinoma; CIN; integration; disruption; deletion; El; E2; survival; inverse PCR; episomal DNA; FISH; chromosomal location;

    Sammanfattning : The general aim of these studies was to define the role of infection with oncogenic human papillomaviruses (HPV) for development of cervical dysplasia and to obtain early molecular markers for progression to carcinoma. The results of cytological screening of 500 women in the Stockholm Gynaecologic Health Control were compared with HPV detection by polymerase chain reaction (PCR) and in situ hybridisation (ISH). LÄS MER