Sökning: "immune reactivity"

Visar resultat 11 - 15 av 152 avhandlingar innehållade orden immune reactivity.

  1. 11. Genetic and functional analysis of the adaptive immune response

    Författare :Marco Mandolesi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The cells of the adaptive immune system rely on somatic recombination of V, D and J genes to obtain a vast range of specificities. T cells use four chains encoded by three genomic loci, to produce alpha/beta or gamma/delta T cell receptors (TCRs). LÄS MER

  3. 12. Biliary epithelial cells, the immune system and PSC pathogenesis

    Författare :Lena Berglin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Primary sclerosing cholangitis (PSC) is a chronic, inflammatory liver disease that leads to destruction of the bile duct system. PSC is strongly associated with inflammatory bowel disease, and PSC patients have an increased risk of developing malignancies, especially cholangiocarcinoma (CCA). LÄS MER

  4. 13. Immune regulation and modulation of allergy and inflammatory diseases

    Författare :Jeanette Grundström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Inflammation is evoked in defence against invading pathogens entering the body. Sometimes inflammation is started against harmless antigens, which leads to allergic diseases, or against self-antigens or commensal microbiota as in inflammatory bowel disease (IBD). LÄS MER

  5. 14. Human cytomegalovirus (HCMV) : detection and elimination of infected blood cells in vitro, immune reactivity and complications following HCMV infection

    Författare :Susanne Larsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human cytomegalovirus (HCMV) belongs to the herpes virus family and establishes life-long persistence in a latent state following a primary infection. HCMV disease causes high morbidity in immunosuppressed individuals, such as bone marrow and organ transplant patients. LÄS MER

  7. 15. On the etiology and pathogenesis of systemic lupus erythematosus with special reference to environmental factors

    Författare :Anders Bengtsson; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi; Skeleton; Risk factors; Human parvovirus B19; Immune complex; Disease activity; Interferon-alpha; SLE; Retrovirus;

    Sammanfattning : Systemic lupus erythematosus (SLE) is a complex autoimmune disease in which environmental factors interact with genetic factors in the development of the disease process and evolution of clinical manifestations. In this thesis both exogenous factors and host factors were investigated, as well as important immunopathological aspects including involvement of immune complex (IC), the complement system and interferon-alpha (IFN-α). LÄS MER