Sökning: "growth hormone deficiency"

Visar resultat 6 - 10 av 46 avhandlingar innehållade orden growth hormone deficiency.

1. 6. Effects of growth hormone on cardiovascular risk factors and atherosclerosis

   Författare :Maria Leonsson Zachrisson; Göteborgs universitet; []
   Nyckelord :growth hormone; pituitary deficiency; dietary fat; cholesterol; low density; lipoprotein; intima-media thickness; IL-6; CRP; TNF-á;

   Sammanfattning : Hypopituitary patients with growth hormone (GH) deficiency (GHD) have increasedmorbidity and mortality from cardiovascular disease (CVD). GH treatment has both beneficialand potentially negative cardiovascular effects. LÄS MER

3. 7. Cardiovascular mortality and morbidity in hypopituitary patients and metabolic effects of growth hormone treatment

   Författare :Birgitta Bulow; Lund Medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glucose metabolism; growth hormone replacement; growth hormone deficiency; long-term survival; craniopharyngioma; cardiovascular risk factors; Hypopituitarism; cardiovascular mortality; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

   Sammanfattning : Premature atherosclerosis, cardiovascular risk factors and increased cardiovascular mortality have been shown in patients with hypopituitarism on conventional hormone treatment, but without growth hormone (GH) replacement. The aims of paper I-III were to investigate separately the risks for cerebrovascular and cardiac mortality as well as the incidence of cardiovascular disease in patients with hypopituitarism and to assess the long-term prognosis for patients with craniopharyngioma. LÄS MER

4. 8. Bone health and cardiovascular risk in hypopituitary patients on complete hormone replacement, including GH

   Författare :Helene Holmer; Lund Medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sekretion; diabetologi; Endokrinologi; Craniopharyngioma; insulin tolerance test; Endocrinology; secreting systems; diabetology; cardiovascular risk; growth hormone deficiency; fracture incidence; bone mineral density; growth hormone replacement;

   Sammanfattning : Growth hormone deficiency (GHD) is associated with decreased bone mineral density (BMD). Low BMD is correlated to increased fracture risk. There are no studies on fracture risk in GHD patients on GH therapy and no studies on BMD in adults with childhood onset (CO) craniopharyngioma (CP) on GH therapy. LÄS MER

5. 9. Late complications of childhood acute lymphoblastic leukaemia (ALL), with special reference to hormone secretion, cardiovascular risk and bone health

   Författare :Cecilia Follin; Lund Medicin; []
   Nyckelord :growth hormone treatment; growth hormone deficiency; cranial radiotherapy; Acute lymphoblastic leukaemia; cardiovascular risk factors; bone mineral density; prolactininsufficiency;

   Sammanfattning : An increased prevalence of cardiovascular (CV) risk factors and cardiac abnormalities has been shown among adult GH deficient ALL survivors subjected to cranial irradiation. The ALL treatment includes many known risk factors for low bone mineral density (BMD), but little is known about pituitary insufficiencies, except for GH deficiency. LÄS MER

7. 10. Childhood malignant disease and consequences for growth hormone secretion, intellectual function and cardiovascular risk

   Författare :Katarina Link; Lund Medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone deficiency; Insulin sensitivity; Cranial radiotherapy; Neuropsychological performance; Endocrinology; secreting systems; diabetology; Acute Lymphoblastic leukemia; diabetologi; sekretion; Endokrinologi;

   Sammanfattning : In childhood onset growth hormone deficiency (GHD) a reduction in cardiac left ventricular mass (LVMi) and impairment of cardiac systolic function, as well as in glomerular filtration rate (GFR) has been shown. In study I, we showed that a low dose of GH treatment for 10 months resulted in increased LVMi and kidney size. LÄS MER