Sökning: "gap junctional coupling."

Hittade 4 avhandlingar innehållade orden gap junctional coupling..

  1. 1. Connexin43 in astroglial gap junctions. Regulation by age, neurotransmitters, GH and IGF-I

    Författare :N David Åberg; Göteborgs universitet; []
    Nyckelord :Connexin43; rat; development; hypophysectomy; primary culture; ; mRNA; gap junction; somatotropin; IGF-I; serotonin; glutamate; ; brain region heterogeneity; calcium wave; astrocyte; astroglial cell; ; gap junctional coupling.;

    Sammanfattning : Connexins form gap junctions that are aqueous pores allowing low-molecular (.... LÄS MER

  3. 2. Neural stem cell engraftment : functional interactions, brain repair and gap junctions

    Författare :Johan Jäderstad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neural stem cell (NSC) engraftment therapies show increasing promise as potential cures for several of the diseases of the central nervous system. Traditionally, functional improvements after NSC engraftment have been attributed to replacement of lost neurons and astrocytes, remyelination and support of adjacent cells at risk. LÄS MER

  4. 3. Stem cell interactions with the injured brain

    Författare :Linda Maria Jäderstad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neurodegenerative diseases such as Parkinson's disease, Huntington's disease and amyotrophic lateral sclerosis and acute neurological disorders such as brain ischemia and traumatic injury yearly affect millions of people. Neural stem cell (NSC) grafting is an emerging strategy to treat and potentially cure these conditions for which today no effective remedies exist. LÄS MER

  5. 4. Mechanisms for leukocyte-mediated adjustment of endothelial barrier function

    Författare :Narinder Gautam; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Inflammation; leukocyte extravasation; endothelial cells; vascular permeability; plasma leakage integrin signaling; heparin binding protein; contact phase; bradykinin.;

    Sammanfattning : Extravasation of polymorphonuclear leukocytes (PMN) and associated plasma exsudation are key events in the inflammatory process. The mechanism by which activated PMN may induce increased vascular permeability for macromolecules is not fully understood but crucially dependent on an intact leukocytic beta2 integrin (CD11/CD18) adhesion receptor function. LÄS MER