Sökning: "hypophysectomy"
Visar resultat 1 - 5 av 8 avhandlingar innehållade ordet hypophysectomy.
1. GH/IGF-I axis regulation of cardiovascular and neuronal gene expression and function
Sammanfattning : Abstract Cardiovascular disease is a major cause of mortality in the Western world. Another important clinical condition is brain damage due to radiation therapy in cancer patients. This has neurological impairments presenting in the survivors. For both these conditions, it is important to develop new therapeutic strategies. LÄS MER
2. Connexin43 in astroglial gap junctions. Regulation by age, neurotransmitters, GH and IGF-I
Sammanfattning : Connexins form gap junctions that are aqueous pores allowing low-molecular (.... LÄS MER
3. The interplay between the endocrine and cardiovascular systems. A study of the hormonal influence on cardiovascular function and endothelial nitric oxide synthase (eNOS) expression
Sammanfattning : During the present thesis, special interest was focused on the cardiovascular effects of growth hormone (GH) and estrogen (E2) and combined treatment of GH+E2, in particular the possible effects on endothelial nitric oxide synthase (eNOS) expression and nitric oxide (NO) bioavailability for maintaining cardiovascular homeostasis. The possible role of fluid mechanical force e. LÄS MER
4. Hormonal regulation of hepatic cholesterol and lipoprotein metabolism : effects of estrogen and growth hormone
Sammanfattning : Coronary heart disease is the result of the progression of atherosclerotic lesions, and represents the major cause of death in western countries. Age, male sex, plasma cholesterol, hypertension and smoking are major risk factors for atherosclerosis. LÄS MER
5. Growth hormone regulation of LFABP and PPARa. Genes involved in hepatic lipid metabolism
Sammanfattning : Growth hormone (GH) is known to have several important effects in the control of metabolism. The aim of these studies was to investigate how GH regulates genes involved in fatty acid transport and metabolism in the liver and the interaction between GH and fatty acids in this regulation. LÄS MER