Sökning: "Narinder Gautam"

Hittade 1 avhandling innehållade orden Narinder Gautam.

1. 1. Mechanisms for leukocyte-mediated adjustment of endothelial barrier function

   Författare :Narinder Gautam; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Inflammation; leukocyte extravasation; endothelial cells; vascular permeability; plasma leakage integrin signaling; heparin binding protein; contact phase; bradykinin.;

   Sammanfattning : Extravasation of polymorphonuclear leukocytes (PMN) and associated plasma exsudation are key events in the inflammatory process. The mechanism by which activated PMN may induce increased vascular permeability for macromolecules is not fully understood but crucially dependent on an intact leukocytic beta2 integrin (CD11/CD18) adhesion receptor function. LÄS MER