Sökning: "epitopemapping"

Hittade 1 avhandling innehållade ordet epitopemapping.

1. 1. Autoantigenic properties of the U1-70K protein

   Författare :Elisabet Welin Henriksson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :U1-70K protein; ribonucleoproteins; autoantigens; autoantibodies; epitopemapping; connective tissue disease; species specificity; cross reactions; amino acidsequence; recombinant proteins; mutagenesis;

   Sammanfattning : Patients with the autoimmune diseases systemic lupus erythematosus and mixed connective tissue disease produce autoantibodies directed towards specific groups of cellular constituents in their own body. Two of the targeted antigens are denoted Sm and RNP, and consist of distinct collections of splicing associated RNA-protein complexes. LÄS MER