Sökning: "de novo"

Visar resultat 21 - 25 av 343 avhandlingar innehållade orden de novo.

  1. 21. Phasing single DNA molecules with barcode linked sequencing

    Författare :David Redin; Afshin Ahmadian; Ulf Gyllensten; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Single molecule sequencing; DNA barcoding; whole genome haplotyping; linked-read sequencing; phasing; de novo genome assembly.; Biotechnology; Bioteknologi;

    Sammanfattning : Elucidation of our genetic constituents has in the past decade predominately taken the form of short-read DNA sequencing. Revolutionary technology developments have enabled vast amounts of biological information to be obtained, but from a medical standpoint it has yet to live up to the promise of associating individual genotypes to phenotypic states of wide-spread clinical relevance. LÄS MER

  3. 22. Genome sequencing. Analysis of pathogenicity factors in hereditary and bacterial diseases

    Författare :Joakim Westberg; KTH; []
    Nyckelord :genome sequencing; DNA sequencing; dye-terminator; solid-phase; de novo mutation detection; Mycoplasma mycoides subsp. mycoides SC; mycoplasma; CBPP; properdin; insertion sequence; ISMmy1;

    Sammanfattning : With a metal removal process based on precipitation aimed atthe purification of pulping effluent as a starting point, theinfluence of carboxylic acids on calcium carbonateprecipitation has been studied. The chosen carboxylic acids canact as more or less strong complexing agents for aqueouscalcium, just as many compounds found in pulping liquors. LÄS MER

  4. 23. Disputatio philosophica inauguralis de notitia sui sive de homine, ... sub pr�side ... M. Johanne L. Staleno, ... auctore & respondente Israele Israelis F. Lincopi� Gotho. In auditorio novo ad d. 25. Maij, horis matutinis

    Författare :Johannes Laurentii Stalenus; Israel Israelis Fortelius; Johannes Laurentii Stalenus; Uppsala universitet; []
    Nyckelord :HUMANIORA; HUMANITIES;

    Sammanfattning : .... LÄS MER

  5. 24. Dissertatio de mansvetudine seu regenda ira, quam ... sub præsidio Erici Matthiæ Roslagii ... suscepit Johannes Kempe. In audit. novo ad diem 5. mart. anno 1642

    Författare :Eric Matthiæ; Johannes Kempe; Eric Matthiæ; Uppsala universitet; []
    Nyckelord :HUMANIORA; HUMANITIES;

    Sammanfattning : .... LÄS MER

  7. 25. Protein kinases in hormonal regulation of adipocyte metabolism

    Författare :Christine Berggreen; Proteinfosforylering; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adipocyte; PKB; AMPK; SIK3; insulin; catecholamines; lipolysis; lipogenesis; glucose uptake; de novo fatty acid synthesis; A769662; Akti; cAMP;

    Sammanfattning : Abstract Along with liver and muscle tissue, adipose tissue helps maintain normal levels of glucose and lipids in the blood and has a very important role when it comes to storing lipids that can provide whole-body energy. After a meal is ingested, adipocytes take up glucose from the circulation and use it as a substrate for synthesis of new fatty acids (FAs) in a process known as de novo fatty acid synthesis, as well as for synthesis of glycerol. LÄS MER