Sökning: "coupled calculations"
Visar resultat 1 - 5 av 122 avhandlingar innehållade orden coupled calculations.
1. Development and Applications of a General Coupled Thermal-hydraulic/Neutronic Model for the
Sammanfattning : Coupled calculations are important for the simulation of nuclear power plants when there is a strongfeedback between the neutron kineticsand the thermal-hydraulics. A general coupled model of the Ringhals-3 Pressurized Water Reactor has beendeveloped for this purpose. LÄS MER
2. Free energy calculations of G protein-coupled receptor modulation : New methods and applications
Sammanfattning : G protein-coupled receptors (GPCRs) are membrane proteins that transduce the signals of extracellular ligands, such as hormones, neurotransmitters and metabolites, through an intracellular response via G proteins. They are abundant in human physiology and approximately 34% of the marketed drugs target a GPCR. LÄS MER
3. Development of fine-mesh methodologies for coupled calculations in Light Water Reactors
Sammanfattning : This thesis presents fine-mesh multiphysics methodologies and algorithms for numerical predictions of the behavior of Light Water Reactor (LWR) cores. The multiphysics aspects cover the distribution of neutrons, the fluid flow of the coolant and the conjugate heat transfer between the solid fuel pins and the fluid coolant. LÄS MER
4. Development of an integrated neutronic/thermal-hydraulic tool for estimating fluctuations in PWRs
Sammanfattning : Monitoring and diagnostics of a reactor core at a given state is very important for detecting potential problems and anomalies at an early stage. Several methods exist for these purposes, but the majority of them require a disruption of the plant operation, e.g. by shut-down or by perturbation of the system. LÄS MER
5. Molecular simulations of G protein-coupled receptors : A journey into structure-based ligand design and receptor function
Sammanfattning : The superfamily of G protein-coupled receptors (GPCRs) contains a large number of important drug targets. These cell surface receptors recognize extracellular signaling molecules, which stimulates intracellular pathways that play major roles in human physiology. LÄS MER