Sökning: "clinical trial analysis"

Visar resultat 16 - 20 av 327 avhandlingar innehållade orden clinical trial analysis.

  1. 16. Ultrasound measurements of subclinical carotid atherosclerosis : methodological and clinical studies

    Författare :Emma Nyman; Christer Grönlund; Ulf Näslund; Isabel Gonçalves; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atherosclerosis; ultrasound; carotid artery; carotid intima media thickness; carotid plaque; reproducibility; intervention; echogenicity; cardiovascular disease; hjärt- och kärlforskning;

    Sammanfattning : Ultrasound measurements of subclinical carotid atherosclerosis have been evaluated as an additional parameter in risk evaluation of cardiovascular diseases (CVD). The overall aim of this thesis was to increase knowledge regarding ultrasound measurements of subclinical carotid atherosclerosis. LÄS MER

  3. 17. Novel immunotherapies for metastatic uveal melanoma - From bench to clinical biomarkers

    Författare :Vasu R. Sah; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Immunotherapy has revolutionized cancer treatment, with durable long-term effects in a proportion of patients. However, in around half of these patients, there are little to no effects. Patients with metastatic uveal melanoma (mUM), a rare form of melanoma originating from the eye has lack of effective treatments. LÄS MER

  4. 18. Meta-analysis of randomized clinical evidence of chemotherapy, radiotherapy and endocrine therapy in breast cancer

    Författare :Antonis Valachis; Vassilios Georgoulias; Dimitros Mavroudis; Gregory Chouverakis; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Meta -analysis; Bisphosphonates; Bevacizumab; Trastuzumab; Fulvestrant;

    Sammanfattning :  Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in females worldwide. Despite the growing body of randomized controlled trials (RCTs) regarding the use of various treatment strategies (chemotherapy, endocrine therapy, radiotherapy) in breast cancer, the efficacy of some strategies remains unclear and questionable. LÄS MER

  5. 19. Implementation of gut-directed hypnotherapy for irritable bowel syndrome in clinical practice

    Författare :Perjohan Lindfors; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IBS; Gut-directed Hypnotherapy; Patient satisfaction; GI motility;

    Sammanfattning : Background: Irritable Bowel Syndrome (IBS) is characterized by recurrent abdominal pain or discomfort, related to abnormal bowel habits. This benign and common condition is in severe cases associated with bothersome GI symptoms, decreased quality of life and psychological comorbidity. LÄS MER

  7. 20. Biological and histological factors as predictors in rectal cancer patients : A study in a clinical trial of preoperative radiotherapy

    Författare :Annica Holmqvist; Xiao-Feng Sun; Gunnar Adell; Jan-Erik Frödin; Östergötlands Läns Landsting; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Onkologi;

    Sammanfattning : With improved surgical techniques and preoperative radiotherapy (RT) the local recurrence rate in rectal cancer patients has been reduced, however the mortality rate is still high and there is a huge variation in the response to preoperative RT in patients with the same tumour stage. To improve patient’s survival, it is of great importance to identify good prognostic and predictive factors that help us to select the best suited patients for preoperative RT in the future. LÄS MER