Sökning: "biobank quality"

Visar resultat 11 - 15 av 15 avhandlingar innehållade orden biobank quality.

1. 11. Fatigue and Peripheral Muscle Dysfunction: Studies on Vitamin D Status, Muscle Metabolism and Systemic Inflammation in Patients with COPD : Aspects of COPD severity beyond FEV1 and exacerbations

   Författare :Magnus Kentson; Lennart Persson; Jan-Erik Karlsson; Fredrik Nyström; Arne Egesten; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : BackgroundThe severity of Chronic Obstructive Pulmonary Disease (COPD) is usually described in terms of forced expiratory volume in one second (FEV1) and number of exacerbations. However, COPD is a complex disease with different ways of expression, involving pulmonary symptoms, extra pulmonal manifestations and comorbidities, which altogether affect the patient by contributing to reduced functional capacity, increased shortness of breath, reduced health-related quality of life and increased mortality. LÄS MER

3. 12. Investigating mental health disorders in relation to job and living related factors

   Författare :Salahuddin Mohammad; Jessica Mwinyi; Helgi B. Schiöth; Katarina Laurell; Kent W. Nilsson; Jussi Jokinen; Gustaf Gredebäck; Kristiina Tammimies; Giorgia Bussu; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mental health; job satisfaction; job tenure; Autism spectrum disorder; well-being; genetic risk score; Psychiatry; Psykiatri; Medicinsk vetenskap; Medical Science; Medicinsk genetik; Medical Genetics; Occupational and Environmental Medicine; Arbets- och miljömedicin;

   Sammanfattning : Job satisfaction plays an important role for life quality and health of working individuals. While studies have shown that self-reported mental health conditions such as stress, anxiety and depression are associated with job satisfaction, a large population-based study exploring and comparing self-reported physician posed diagnosed conditions and their association with job satisfaction and job tenure is missing. LÄS MER

4. 13. Discovery and validation of protein biomarkers for lung cancer

   Författare :Luigi De Petris; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Lung cancer is a disease characterized by high incidence and mortality rates as well as by a remarkable resistance to common treatment strategies. Reliable and validated biomarkers could represent a possible breakthrough in the management of this tumor type, by facilitating diagnosis, refining prognosis and providing guidance towards the choice of the most appropriate therapy. LÄS MER

5. 14. Identification and functional characterization of irritable bowel syndrome (IBS) risk genes and variants

   Författare :Tenghao Zheng; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : As one of the most prevalent functional gastrointestinal disorders (FGIDs), irritable bowel syndrome (IBS) affects more than 10% of the general population worldwide with a higher prevalence in women. The primary clinical manifestation of IBS is chronic abdominal pain or discomfort associated with changes in stool frequency and appearance. LÄS MER

7. 15. Establishment of new potential biomarkers for cardiometabolic diseases

   Författare :Karin Littmann; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Cardiometabolic diseases is a growing health issue worldwide. New knowledge about the pathophysiological processes have been gained and several research discoveries have contributed to better management of the diseases. Even so, the prognosis, diagnosis, and treatment of cardiometabolic diseases needs to be further improved. LÄS MER