Sökning: "bacterial pathogenesis"

Visar resultat 16 - 20 av 146 avhandlingar innehållade orden bacterial pathogenesis.

  1. 16. Type III secretion- the various functions of the translocon operon in bacterial pathogenesis

    Författare :Jeanette E Bröms; Åke Forsberg; Michael Koomey; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Yersinia; Pseudomonas aeruginosa; type III secretion; chaperone; translocation; regulation; lcrGVHyopBD; pcrGVHpopBD; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : In order to establish colonisation of a human host, pathogenic Yersinia use a type III protein secretion system to directly intoxicate host immune cells. Activation of this system requires target cell contact and is a highly regulated process. LÄS MER

  3. 17. Bacterial physiology and its role in antibiotic refractoriness

    Författare :Spyridon Gkotzis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The pathological outcome of a bacterial infection depends on the interplay among the host’s innate defenses, the virulence arsenal of the pathogen and antibiotic treatment strategies. Understanding this interplay will provide mechanistic insights on antibiotic pharmacodynamics and bacterial pathogenesis, and set the stage for the development of novel therapeutic interventions. LÄS MER

  4. 18. Macrophage programming and host responses to bacterial infection

    Författare :Xiao Wang; Hong Sjölinder; Martin Rottenberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Macrophages; meningococci; mycobacteria; NhhA; CD46; cytokines; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Macrophages are dynamic, plastic, and heterogeneous immune cells that play an important role in host immune defense against bacterial infection. Various bacterial pathogens, such as Neisseria meningitidis and Mycobacterium tuberculosis, can modulate host immune responses by interfering with macrophage differentiation and polarization. LÄS MER

  5. 19. Pathogenesis and immunotherapy of streptococcal septicemia and shock

    Författare :Nahla Ihendyane; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Streptococcus; Cytokines; Superantigens; Sepsis; Inflammation; IVIG;

    Sammanfattning : Streptococei have been recognized as important causes of severe sepsis. Increased frequencies of streptococcal toxic shock syndrome caused by group A streptococcus (GAS) have been noted worldwide during the last 15 years. LÄS MER

  7. 20. Towards a bacterial origin of irritable bowel syndrome

    Författare :Aldona Dlugosz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Chlamydia;

    Sammanfattning : Background: The irritable bowel syndrome (IBS) is one of the most prevalent disorders and affects about 15% of the Swedish population. Patients with IBS suffer from abdominal pain and disturbed bowel function. Despite being so common, little is known about causality in IBS. LÄS MER