Sökning: "vasorelaxant activity"

Hittade 4 avhandlingar innehållade orden vasorelaxant activity.

  1. 1. Biologically Interesting Compounds from Natural Sources

    Författare :Veronica de la Parra; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cytotoxicity; Natural products; terpenoids; vasorelaxant activity; allylmercaptane; diabetes mellitus type II; Organisk kemi; Organic chemistry; Cacalia decomposita; GPR40 receptor; TRP channel;

    Sammanfattning : Natural products have traditionally played a major role in the drug discovery process. Besides constituting extremely popular drugs in the market, and an ever-increasing source of interesting and novel chemical structures, they have also aided the characterization of many a pharmacological target. LÄS MER

  3. 2. Harvesting of Saphenous Vein for Coronary Artery Bypass Grafting : An Improved Technique that Maintains Vein Wall Integrity and Provides a High Early Patency Rate

    Författare :Domingos Souza; Kjell Rådegran; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Saphenous vein; coronary bypass; endothelium; nitric oxide; patency rate; Kirurgi; Surgery; Kirurgi; Thoracic and Cardivascular Suregery; kirurgi; särskilt thoraxkirurgi;

    Sammanfattning : The primary aim of this thesis was to modify saphenous vein (SV) harvesting technique and evaluate its clinical importance. A new "no touch" (NT) technique of SV preparation was developed where the vein is harvested with a pedicle of surrounding tissue, which protects the vein from spasm therefore obviating the need for distension. LÄS MER

  4. 3. Studies on incretins and cardiovascular function

    Författare :David Nathanson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Type 2 diabetes (T2DM) is a strong risk factor for coronary heart disease (CHD). A great many diabetic subjects suffer from congestive heart failure (CHF), a condition with a high concomitant mortality. So far, attempts aimed at reducing macrovascular complications in T2DM have been essentially futile. LÄS MER

  5. 4. Role of GLP-1 receptor agonists in endothelial function

    Författare :Özlem Erdogdu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Type 2 diabetes;

    Sammanfattning : BACKGROUND: The leading cause of death for patients suffering from type 2 diabetes is macrovascular disease. Endothelial dysfunction is one of the earliest events identified in the pathogenesis of atherosclerosis. Hence, there is a need for finding glucose-lowering agents that cause direct positive effects on vasculature in diabetic patients. LÄS MER