Sökning: "annelie pamren"

Hittade 1 avhandling innehållade orden annelie pamren.

  1. 1. Different types of γ-secretes complexes and their effect on substrate processing

    Författare :Annelie Pamrén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The γ-secretase complex is a transmembrane aspartyl protease that generates the Alzheimer disease (AD) related amyloid β-peptide (Aβ) from the amyloid precursor protein (APP). The γ-secretase complex cleaves APP at two different sites (γ- and ε-sites) generating Aβ-peptides and the APP intracellular domain (AICD). LÄS MER