Sökning: "amyloid β-peptide"

Visar resultat 36 - 37 av 37 avhandlingar innehållade orden amyloid β-peptide.

  1. 36. Identification and investigation of gamma-secretase associated proteins from brain

    Författare :Yasuhiro Teranishi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Alzheimer disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia. The pathological hallmarks in the AD brain are extracellular deposition of amyloid plaques, mainly composed of the amyloid β-peptide (Aβ), and intracellular neurofibrillary tangles made of hyperphosphorylated tau. LÄS MER

  3. 37. Omega-3 fatty acid treatment in mild to moderate Alzheimer's disease : results from the OmegAD study

    Författare :Yvonne Freund-Levi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Alzheimer s disease; progressive neurodegenerative disease; omega-3 fatty acid n-3 FA docosahexaenoic acid; DHA; eicosapentatenoic acid; EPA; linoleic acid; LA; acetylcholinesterase inhibitors; AChEI; Minimental State Examination; MMSE; ADAS-cog; Clinical Dementia Rating scale; CDR; Neuropsychiatric Inventory; NPI; Montgomery Åsberg Depression Rating scale; MADRS; Disability Assessment for Dementia; DAD; Care givers burden CGB; APOEε4; hs-CRP; IL-6; TNF-α and sIL-RII; Aβ42; T-tau and P-tau; weight; Body Mass Index; BMI.;

    Sammanfattning : Alzheimer's disease (AD) is a major public health concern in all countries with an increasing prevalence. It is expected to quadruple by the year 2047. LÄS MER