Sökning: "Valvular heart disease"

Visar resultat 21 - 25 av 26 avhandlingar innehållade orden Valvular heart disease.

  1. 21. Molecular mechanisms of cardiovascular calcification

    Författare :Miguel Carracedo Ortiz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cardiovascular calcification is a pathophysiological process characterized by the deposition of calcium-phosphate crystals in the arteries and the leaflets of the heart valves. In the arteries calcification causes arterial stiffness, which may lead to poor cardiac perfusion, systolic hypertension and heart failure. LÄS MER

  2. 22. Atrial fibrillation : clinical managements with special emphasis on cardioversion

    Författare :Viveka Frykman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Atrial fibrillation; antiarrhythmic treatment; anticoagulation; cardioversion; defibrillation threshold; efficacy; energy requirement; guidelines; internal defibrillation; left ventricular dysfunction; management; safety; symptoms.;

    Sammanfattning : Atrial fibrillation (AF) is the most common arrhythmia of clinical importance. It often decreases quality of life and is related to significant morbidity, as well as decreases longevity. LÄS MER

  3. 23. Drug safety and effectiveness in relation to kidney function : a pharmacoepidemiological approach

    Författare :Marco Trevisan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Kidney function plays an important role in drug safety and effectiveness. As many medications are excreted by the kidneys, patients with reduced kidney function are at a higher risk of supra-therapeutic or toxic drug levels. LÄS MER

  4. 24. Noninvasive evaluation of the effects of coronary artery bypass grafting on myocardial function

    Författare :Anders Hedman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Coronary artery bypass grafting; C-reactive protein; dobutamine stress test; Doppler tissue imaging; echocardiography; exercise test; interleukin-6; myocardial peifusion scintigraphy.;

    Sammanfattning : Coronary bypass grafting (CABG) is an effective treatment of patients with coronary artery disease and leads to an improvement in both cardiac symptoms and long-term survival. The effects of CA13G on global left ventricular systolic and diastolic function at rest and during stress, and the long-term effects on right ventricular function and their significance and relation to early graft occlusion and residual myocardial ischemia have however not been fully elucidated. LÄS MER

  5. 25. Cardiac Performance, Ventricular-Vascular Interaction and Functional Alterations in Rheumatic Mitral Stenosis : A descriptive study employing novel hemodynamic and echocardiographic modalities

    Författare :Ashwin Venkateshvaran; Lars-Åke Brodin; Per Lindquist; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Tillämpad medicinsk teknik; Applied Medical Technology;

    Sammanfattning : The assessment of LV performance poses significant challenges in the setting of rheumatic mitral stenosis (MS) owing to an inherently load-altered state. A detailed characterization of arterial-ventricular coupling between subjects with isolated post-capillary pulmonary hypertension (Ipc-PH) and combined pre- and post-capillary pulmonary hypertension (Cpc-PH) has not been described. LÄS MER