Sökning: "Kynurenine"

Visar resultat 1 - 5 av 40 avhandlingar innehållade ordet Kynurenine.

  1. 1. Non-invasive monitoring of low molecular weight biomarkers relevant to skin inflammation and cancer

    Författare :Skaidre Jankovskaja; Tautgirdas Ruzgas; Johan Engblom; György Marko-Varga; Melinda Rezeli; Pawel Lukasz Urban; Malmö universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tryptophan; Kynurenine; Phenylalanine; Tyrosine; Low molecular Weight Biomarkers; Non-Invasive; Skin Surface Sampling; Skin Permeability; Hydrogels; Prussian White; Health and society; Hälsa och samhälle;

    Sammanfattning : Development of skin inflammation and cancer in viable epidermis and dermis involve slow molecular weight (LMW) metabolites. We hypothesize that these LMW compounds can be collected on the surface of the skin and used for non-invasive diagnostics of skin disorders. LÄS MER

  3. 2. Inflammatory activation of the kynurenine pathway : studies with lipopolysaccharides

    Författare :Anthi Faka Schulte; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neuroinflammation is increasingly recognised as playing an important role in several major psychiatric disorders. The mechanisms by which neuroinflammation influences neurotransmitter systems have for long been unknown. LÄS MER

  4. 3. Bridging immune activation with the kynurenine pathway : implications for psychosis

    Författare :Markus Larsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Kynurenic acid (KYNA), an endogenous N-Methyl-D-aspartic acid receptor (NMDAR) antagonist, is elevated in patients with schizophrenia. In addition, elevated levels of KYNA are associated with activation of the immune system, which also has been implicated in the development and maintenance of psychotic disorders, including schizophrenia. LÄS MER

  5. 4. Dysregulation of the kynurenine pathway in psychotic disorders : immunological aspects

    Författare :Magdalena Kegel; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Kynurenic acid (KYNA), a metabolite of the kynurenine pathway, is emerging as a key factor in the development of psychotic disorders. Increased levels of KYNA are found in the brain and cerebrospinal fluid (CSF) of patients with schizophrenia and bipolar disorder, and are associated to psychotic symptoms. LÄS MER

  7. 5. Inflamed Depression - Origin, Essence, and Remedies

    Författare :Klara Suneson; Lund Psykiatri; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Depression; Inflammation; Omega-3 fatty acids; Kynurenine pathway; Phenotypes; Selective serotonin reuptake inhibitor SSRI ;

    Sammanfattning : .... LÄS MER