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1. 1. Cyanoacetylation of indoles, pyrroles and amines, and synthetic uses of these products

   Författare :Johnny Slätt; Jan Bergman; David Erlinge; Tomas Hedner; Michael Begtrup; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Indole; pyrrole; reduction; oxidation; indoline; acylation; cyanoacetylation;

   Sammanfattning : This thesis is based on an organic synthetic project aimed towards development of small molecules acting on the P2 receptor as well as development of synthetic methods to such molecules (primarily indoles and featuring isatogens in particular). The new methodology includes cyanoacetylation of indoles, pyrroles, amines, and enamines using cyanoacetic acid in acetic anhydride. LÄS MER