Sökning: "David Erlinge"
Hittade 5 avhandlingar innehållade orden David Erlinge.
1. Management and Outcome in Non ST-Elevation Acute Coronary Syndromes : Similarities and Differences Between Women and Men
Sammanfattning : Background: Non ST-elevation Acute Coronary Syndromes are the most frequent manifestations of acute ischemic heart disease. Gender differences in treatment intensity, including differences in level of care, have been reported. Also differences in benefit from certain treatments, especially invasive treatment, have been discussed. LÄS MER
Sammanfattning : Background In the event of an acute coronary syndrome (ACS), the risk of death and complications such as stroke and re-infarction is high during the first month. Diabetes, impaired kidney function, elevated markers of systemic inflammation and high level of platelet reactivity have all been associated with worsened prognosis in ACS patients. LÄS MER
3. Platelets : with special reference to platelet density subpopulations, stable coronary heart disease and atrial fibrillation
Sammanfattning : The current thesis was divided into two parts. Basic platelet research is the topic of the first section. The subsequent clinical part examines platelet reactivity in stable angina pectoris (AP) and in atrial fibrillation.Platelet heterogeneity was investigated in the first section (papers 1 and 2). LÄS MER
4. Platelets in inflammation : Role of complement protein C1q, C-reactive proteinand toll-like receptors
Sammanfattning : Platelets are proven essential in haemostasis, however, they are now also increasingly recognized as cells with important immunomodulatory properties, e.g. through interaction with leukocytes and several species of bacteria and by release inflammatory mediators upon activation. LÄS MER
Sammanfattning : This thesis is based on an organic synthetic project aimed towards development of small molecules acting on the P2 receptor as well as development of synthetic methods to such molecules (primarily indoles and featuring isatogens in particular). The new methodology includes cyanoacetylation of indoles, pyrroles, amines, and enamines using cyanoacetic acid in acetic anhydride. LÄS MER