Sökning: "Sophia Ceder"

Hittade 1 avhandling innehållade orden Sophia Ceder.

1. 1. Mechanisms of cancer cell death by mutant p53-reactivating compound APR-246

   Författare :Sophia Ceder; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Tumor suppressor TP53 is the most frequently mutated gene in cancer. A majority of TP53 mutations result in a mutant p53 that disrupts its DNA binding capabilities but may also acquire novel gain-of-function activities that contribute to tumor growth. LÄS MER