Sökning: "Somatostatin receptor"

Visar resultat 31 - 35 av 69 avhandlingar innehållade orden Somatostatin receptor.

  1. 31. Receptor-operated signaling pathways in normal and diabetic pancreatic islet cell function

    Författare :Fan Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Loss of glucose-dependent insulin release is an early pathogenetic event in human type 2 diabetes. Impaired glucose-mediated insulin secretion from pancreatic islet β-cells leads to insulin deficiency and thus hyperglycemia. LÄS MER

  3. 32. Somatostatin, dendritic cells and peptide T in psoriasis : a clinical, immunohistochemical and functional study

    Författare :Toomas Talme; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Peptide T is an octapeptide designed to block the CD4 receptor. In a phase 1 study 9 psoriasis patients were treated with 2 mg peptide T i.v. once daily for 28 days and followed for a further 3 months. LÄS MER

  4. 33. Novel Circulating and Tissue Biomarkers for Small Intestine Neuroendocrine Tumors and Lung Carcinoids

    Författare :Tao Cui; Valeria Giandomenico; Kjell Öberg; Apostolos V. Tsolakis; Marco Volante; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small intestine neuroendocrine tumors; lung carcinoids; Ma2 autoantibodies; immunohistochemistry; olfactory receptor 51E1; blood samples; antibody suspension bead array; 小肠神经内分泌肿瘤，肺类癌，Ma2自身抗体，免疫组化，嗅觉受体蛋白51E1， 血液样本，抗体悬浮磁珠阵列; Endokrinologi och Diabetologi; Endocrinology and Diabetology; Lung Medicine; Lungmedicin; Molecular Biology; Molekylärbiologi; Oncology; Onkologi;

    Sammanfattning : Small intestine neuroendocrine tumors (SI-NETs) and lung carcinoids (LCs) are relatively indolent tumors, which originate from neuroendocrine (NE) cells of the diffuse NE system. Metastases can spread before diagnosis. Thus, potential cures become unavailable, which entitles new biomarker development. LÄS MER

  5. 34. Role of corticotropin-releasing factor, somatostatin and leptin in vagal nerve function and control of gastric emptying

    Författare :Ulrika Smedh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The overall aim of this thesis was to study the effects of centrally acting CRF and leptin, and peripherally acting somatostatin on gastric emptying of glucose. Freely moving rats bearing chronic intragastric fistulas received intragastric infusions (1.0 ml/min) of glucose (12.5 % or 25 %) during 6-18 min. LÄS MER

  7. 35. Strategies for optimisation of 177Lu-octreotate therapy – exploring local administration and combination therapy regimens

    Författare :Viktor Sandblom; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peptide receptor radionuclide therapy; PRRT; 177Lu-octreotate; Neuroendocrine tumours; Optimisation; Local administration; Combination therapy;

    Sammanfattning : Neuroendocrine tumours (NETs) are a group of heterogeneous tumour types that originate in hormone-producing organs. Patients with NETs are often diagnosed after the primary tumour has metastasised. LÄS MER