Sökning: "Reactive Metabolite"
Visar resultat 26 - 29 av 29 avhandlingar innehållade orden Reactive Metabolite.
26. Studies on anti-leukemic terpenoids from medicinal mushrooms and marine sponges with ChemGPS-NP-based targets investigation of lead compounds
Sammanfattning : This thesis investigates the anti-leukemic activity of terpenoids isolated from medicinal mushrooms and marine sponges, as well as their possible targets and mechanisms of action.In the first section, we focused on studying the triterpenoidal components of three triterpenoid-enriched medicinal mushrooms Antrodia cinnamomea, Ganoderma lucidum, and Poria cocos, which have been used in folk medicine for centuries and also developed into several contemporary marketed products. LÄS MER
27. Epoxides as Contact Allergens - Formation, Sensitising Potency and Structure-Activity Relationships
Sammanfattning : Chemicals in our environment with which we have repeated skin contact can cause skin sensitisation (contact allergy). To trigger an immune response a compound (hapten) must be able to penetrate the skin, where it needs to be reactive enough to bind to proteins and form immunogenic complexes that are recognised as foreign. LÄS MER
28. Experimental spinal cord injury : development of protection and repair strategies in rats
Sammanfattning : Spinal cord injury typically results in neurological deficits that can not be reversed, often leaving patients bound to a wheelchair. Current treatment strategies are not very successful. Despite many promising experimental strategies, clinical translation has so far been very limited. LÄS MER
29. Studies on the role of HIF-1 in the control of infection with Mycobacterium tuberculosis
Sammanfattning : Mycobacterium tuberculosis (M. tuberculosis), the causative agent of tuberculosis (TB), is responsible for most deaths caused by a bacterium globally. LÄS MER