Sökning: "Prehapten"

Hittade 2 avhandlingar innehållade ordet Prehapten.

  1. 1. Epoxides as Contact Allergens - Formation, Sensitising Potency and Structure-Activity Relationships

    Författare :Ida Belogorcev Niklasson; Göteborgs universitet.; Gothenburg University.; [2013]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Allergic contact dermatitis; Autoxidation; Bioactivation; Cinnamic alcohol; Diglycidyl ether of bisphenol A DGEBA ; Epoxide; Epoxy resin; Local lymph node assay; Polymerisation; Peptide reactivity; Prehapten; Prohapten; Sensitisation; Skin; Structure-Activity Relationship; Thermogravimetric Analysis;

    Sammanfattning : Chemicals in our environment with which we have repeated skin contact can cause skin sensitisation (contact allergy). To trigger an immune response a compound (hapten) must be able to penetrate the skin, where it needs to be reactive enough to bind to proteins and form immunogenic complexes that are recognised as foreign. LÄS MER

  2. 2. Allergenic Oxidation Products from Fragrance Terpenes. Chemical Analysis and Determination of Sensitizing Potency

    Författare :Johanna Rudbäck; Göteborgs universitet.; Gothenburg University.; [2013]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Autoxidation; Contact allergy; Essential oils; Fragrances; Hydroperoxides; Ionization techniques; Mass spectrometry; Prehapten; Sensitization; Skin; Structure-activity relationships; Terpenes;

    Sammanfattning : The ubiquitous presence of fragrance compounds in consumer products has resulted in a high frequency of contact allergy to fragrances in the population. For prevention purposes and according to EU regulations, cosmetics must be labeled when containing the most prominent fragrance allergens in concentrations exceeding 0. LÄS MER