Sökning: "Ida Belogorcev Niklasson"

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  1. 1. Epoxides as Contact Allergens - Formation, Sensitising Potency and Structure-Activity Relationships

    Författare :Ida Belogorcev Niklasson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Allergic contact dermatitis; Autoxidation; Bioactivation; Cinnamic alcohol; Diglycidyl ether of bisphenol A DGEBA ; Epoxide; Epoxy resin; Local lymph node assay; Polymerisation; Peptide reactivity; Prehapten; Prohapten; Sensitisation; Skin; Structure-Activity Relationship; Thermogravimetric Analysis;

    Sammanfattning : Chemicals in our environment with which we have repeated skin contact can cause skin sensitisation (contact allergy). To trigger an immune response a compound (hapten) must be able to penetrate the skin, where it needs to be reactive enough to bind to proteins and form immunogenic complexes that are recognised as foreign. LÄS MER