Sökning: "Nerve agents"

Visar resultat 11 - 15 av 42 avhandlingar innehållade orden Nerve agents.

  1. 11. Clinical and experimental studies on the diaphragm during physiological and pathophysio-logical conditions

    Författare :Antonella Lo Mauro; Peter Frykholm; Andrea Aliverti; Anders Larsson; Stephen Edward Rees; Uppsala universitet; []
    Nyckelord :diaphragm; animal model; phrenic nerve injury; pregnancy; lung transplan- tation; stereotactic body radiation therapy; anesthesia; Clinical Physiology; Klinisk fysiologi;

    Sammanfattning : The diaphragm is the most important respiratory muscle. It separates the thorax from the abdomen and it is innervated by phrenic nerve. LÄS MER

  3. 12. Variations in the regulation of pain genes after nerve injury : with focus on sodium channels

    Författare :Anna-Karin Persson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic neuropathic pain is a burdensome clinical condition that causes major suffering for countless of individuals worldwide. It is characterized by a hyperreactive nervous system with hyperexcitable neurons that fire in the absence of stimuli or at mild stimuli, causing pain. LÄS MER

  4. 13. Opioid-induced cholecystokinin release in the CNS-neurochemical mechanisms and effects of sciatic nerve lesion

    Författare :Henrik Gustafsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cholecystokinin (CCK) and opioid peptides have a similar distribution in the nervous system and CCK has been demonstrated to counteract opioid-induced analgesia at spinal and supraspinal level. An increased spinal release of CCK has been suggested to be a mechanism for the relative resistance to opioid analgesic drug in certain pain conditions following nerve lesions (i. LÄS MER

  5. 14. In Vitro – In Vivo Correlation of Injectable Lipid Formulations

    Författare :Lars Söderberg; Livsmedelsteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; EC 50; erythrocyte; human plasma; lipid injectable formulation; IVIVC; fatty acid; in vitro release; Peripheral nerve block; neurolytic; structure-activity;

    Sammanfattning : In order to develop new pharmaceuticals, to optimize pharmacotherapy and secure patient safety, documentation of the properties of pharmaceutical formulations is a most important process. A significant practical problem associated with pre-clinical evaluation of lipophilic substances with pharmacological properties is their low aqueous solubility. LÄS MER

  7. 15. Expression of stimulatory and inhibitory molecules in interactions between natural killer cells neurons

    Författare :Eva Backström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Nervous system; brain; neuron; NK cells; dorsal root ganglia; hippocampus; NKG2D; RAE 1; MULT1; nerve lesion; influenza virus; MCMV.;

    Sammanfattning : Natural killer (NK) cells are important effector cells of the innate and the early induced immune defense. In the nervous system they appear early during inflammation and have been ascribed a role in clearance of certain viral infections from the brain. NK cells are regulated by multiple signals transmitted via inhibitory and stimulatory receptors. LÄS MER