Sökning: "MCMV."

Hittade 3 avhandlingar innehållade ordet MCMV..

  1. 1. Regulation of NK cell activity : studies of DAP12-associated receptors in immune synapse formation and in responses to cytomegalovirus infection

    Författare :Hanna Sjölin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NK cells; DAP12; MCMV Cytokines; Receptors; Signaling; packages;

    Sammanfattning : Natural killer (NK) cell effector functions are important for innate resistance against tumor cells and viral infections. NK cells display a broad range of inhibitory and activating receptors on the cell surface, which ensure specificity. LÄS MER

  3. 2. Expression of stimulatory and inhibitory molecules in interactions between natural killer cells neurons

    Författare :Eva Backström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Nervous system; brain; neuron; NK cells; dorsal root ganglia; hippocampus; NKG2D; RAE 1; MULT1; nerve lesion; influenza virus; MCMV.;

    Sammanfattning : Natural killer (NK) cells are important effector cells of the innate and the early induced immune defense. In the nervous system they appear early during inflammation and have been ascribed a role in clearance of certain viral infections from the brain. NK cells are regulated by multiple signals transmitted via inhibitory and stimulatory receptors. LÄS MER

  4. 3. Vascular related pathologies in cardiovascular disease and cancer

    Författare :Sharan Ananthaseshan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cardiovascular disease (CVD) and cancer are the leading causes of death worldwide. A damaged endothelium is one of the factors contributing towards these diseases. This thesis focused on understanding the implications of alterations to the physiological endothelium resulting in pathologies related to vascular disease and cancer metastasis. LÄS MER