Sökning: "diaphragm"

Visar resultat 1 - 5 av 52 avhandlingar innehållade ordet diaphragm.

  1. 1. Clinical and experimental studies on the diaphragm during physiological and pathophysio-logical conditions

    Författare :Antonella Lo Mauro; Peter Frykholm; Andrea Aliverti; Anders Larsson; Stephen Edward Rees; Uppsala universitet; []
    Nyckelord :diaphragm; animal model; phrenic nerve injury; pregnancy; lung transplan- tation; stereotactic body radiation therapy; anesthesia; Clinical Physiology; Klinisk fysiologi;

    Sammanfattning : The diaphragm is the most important respiratory muscle. It separates the thorax from the abdomen and it is innervated by phrenic nerve. LÄS MER

  3. 2. Regional Lung Mechanics and Influence of an Active Diaphragm in Experimental Lung Injury

    Författare :Mariangela Pellegrini; Anders Sune Larsson; Göran Hedenstierna; Michael Quintel; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute respiratory distress syndrome; artificial respiration; diaphragm; pulmonary atelectasis; lung imaging; respiratory system; animal model; Fysiologi; Physiology; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Sammanfattning : Despite being an essential life-support strategy in severe respiratory failure, mechanical ventilation can, if not optimally set and monitored, lead to injury of the lung parenchyma and diaphragm. These conditions are called ventilator-induced lung injury and ventilator-induced diaphragmatic dysfunction (VIDD), respectively. LÄS MER

  4. 3. Intensive Care Unit Muscle Wasting : Skeletal Muscle Phenotype and Underlying Molecular Mechanisms

    Författare :Sudhakar Reddy Aare; Larsson Lars; Rooyackers Olav; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute quadriplegic myopathy; gene expression; myosin; heat shock proteins; mechanical ventilation; myostatin; sepsis; corticosteroids; diaphragm; Clinical Neurophysiology; Klinisk neurofysiologi;

    Sammanfattning : Acute quadriplegic myopathy (AQM), or critical illness myopathy, is a common debilitating acquired disorder in critically ill intensive care unit (ICU) patients characterized by generalized muscle wasting and weakness of limb and trunk muscles. A preferential loss of the thick filament protein myosin is considered pathognomonic of this disorder, but the myosin loss is observed relatively late during the disease progression. LÄS MER

  5. 4. Studies of diaphragm fatigue and dysfunction

    Författare :Peter J Radell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Diaphragm function; contractility; fatigue; oxidative metabolism; 31phosphorus nuclear magnetic spectroscopy; ultrasonography; prolonged ventilation; compound muscle action potential; myopathy; electroneurography; muscle fiber; morphology.;

    Sammanfattning : Diaphragm fatigue and dysfunction are important components of acute and chronic respiratory pump failure. We lack knowledge about the nature of diaphragm fatigue and the pathophysiological and morphological changes that occur in the diaphragm after prolonged mechanical ventilation. This thesis studied two aspects of diaphragm function. LÄS MER

  7. 5. Lung aeration and pulmonary gas exchange during general and epidural anaesthesia : Influenced by inspired oxygen concentration and diaphragm shape

    Författare :Adrian Reber; Uppsala universitet; []
    Nyckelord :Medical sciences; Anesthesia: epidural; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Physiology; klinisk fysiologi;

    Sammanfattning : Induction of general anaesthesia causes a rapid decrease in functional residual capacity, which can promote alveolar collapse (atelectasis) and airway closure in dependent lung regions. Mismatching of ventilation and perfusion (VA/Q) in the lungs is accompanied by impairment of pulmonary gas exchange. LÄS MER