Sökning: "Maria Rodriguez Zabala"

Hittade 1 avhandling innehållade orden Maria Rodriguez Zabala.

1. 1. CRISPR Screens Identify Candidate Therapeutic Targets in Leukemia

   Författare :Maria Rodriguez Zabala; Avdelningen för klinisk genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute myeloid leukemia; CRISPR screen; leukemia stem cell; cell surface receptor; metabolism; immunotherapy; CXCR4; GLUT1; TFR1; H2-K1;

   Sammanfattning : Acute myeloid leukemia (AML) is a complex hematological malignancy marked by proliferation of immature myeloid cells with a dismal 5-year survival. A major challenge is the persistence of leukemia stem cells (LSCs) after standard treatment, leading to relapse. LÄS MER