Sökning: "MOLECULE"

Visar resultat 6 - 10 av 1839 avhandlingar innehållade ordet MOLECULE.

  1. 6. Single-­molecule spectroscopy of π-­conjugated polymers

    Författare :Oleg Mirzov; Kemisk fysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; fluorescence lifetime; low temperature; spectral diffusion; blinking; MEH-PPV; Single-molecule spectroscopy; π-conjugated polymers; 2D polarization; Monte Carlo; energy transfer;

    Sammanfattning : When applied to condensed-matter samples of large organic molecules, optical spectroscopy faces the problem of inhomogeneous broadening caused by the diversity of environments and conformations that sample molecules are subjected to. This severely limits the information that can be extracted from optical spectra. LÄS MER

  3. 7. Biomolecular Analysis by Dual-Tag Microarrays and Single Molecule Amplification

    Författare :Olle Ericsson; Ulf Landegren; Mats Nilsson; Edwin Southern; Uppsala universitet; []
    Nyckelord :Molecular medicine; Microarray; proximity ligation; Padlock probe; Rolling circle amplification; Splicing; single molecule; Molekylärmedicin;

    Sammanfattning : Padlock probes and proximity ligation are two powerful molecular tools for detection of nucleic acids and proteins, respectively. Both methods result in the formation of DNA reporter molecules upon recognition of specific target molecules. LÄS MER

  4. 8. The multi-faceted RNA molecule : Characterization and Function in the regulation of Gene Expression

    Författare :Mats Ensterö; Marie Öhman; Jørgen Kjems; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Computational Biology; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : In this thesis I have studied the RNA molecule and its function and characteristics in the regulation of gene expression. I have focused on two events that are important for the regulation of the transcriptome: Translational regulation through micro RNAs; and RNA editing through adenosine deaminations. LÄS MER

  5. 9. Nuclear motion in molecular ions studied with synchrotron radiation and multicoincidence momentum imaging spectrometry

    Författare :Joakim Laksman; Synkrotronljusfysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecule; synchrotron;

    Sammanfattning : A momentum imaging spectrometer optimized for photoionization experiments with synchrotron radiation was built in 2008. The spectrometer is equipped with an electrostatic lens, that focuses the charged dissociation products on to a position-sensitive multi-hit delay line anode. LÄS MER

  7. 10. Modeling normal and malignant hematopoiesis in vitro. To screen for extrinsic regulators and differentiation therapy

    Författare :Simon Hultmark; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; acute myeloid leukaemia; Hematologi; stem cells; differentiation induction; leukaemia; treatment; small molecule drugs; PKC; FLT3; shRNA; small molecule inhibitor; Small Molecule Libraries; MEK ERK pathway; natural product; co-culture; drug screening; combination therapy;

    Sammanfattning : The incredible thing with blood stem cells, also known as hematopoietic stem cells (HSC), is that they can restore normal hematopoiesis in patients that need a new blood system. Since a prerequisite for successful transplantation is immune compatibility, it requires large donor registries to find a suitable match for a recipient. LÄS MER