Sökning: "Rolling circle amplification"
Visar resultat 1 - 5 av 46 avhandlingar innehållade orden Rolling circle amplification.
1. Padlock Probes and Rolling Circle Amplification : New Possibilities for Sensitive Gene Detection
Sammanfattning : A series of novel methods for detection of known sequence variants in DNA, in particular single nucleotide polymorphism, using padlock probes and rolling circle replication are presented. DNA probes that can be circularized – padlock probes – are ideal for rolling circle replication. LÄS MER
2. Visual and magnetic detection of antimicrobial resistance genes using nanoparticles and isothermal amplification
Sammanfattning : Antibiotic resistance is becoming an increasing concern, necessitating new ways to diagnose and treat it rapidly and accurately. One proposed solution is the use of nucleic acid amplification tests, capable of detecting resistance in just a few hours, as opposed to the several days that traditional testing methods may require. LÄS MER
3. Padlock Probe-Based Nucleic Acid Amplification Tests : Point-of-care Diagnostics of Infectious Diseases
Sammanfattning : Recent advancements in molecular biology and biotechnology have pushed the field of molecular diagnostics much further to benefit the society towards smart access for rapid and simplified health care. In this context, point-of-care (PoC) technologies that bring the inventions in diagnostics closer to bedside settings draw attention. LÄS MER
4. Genetic Analyses using Rolling Circle or PCR Amplified Padlock Probes
Sammanfattning : Padlock probes are useful in a variety of genetic applications, some of which require that the probes are amplified in order to generate detectable signals. Two general padlock amplification methods, RCA and PCR, are discussed in this thesis. LÄS MER
5. Advancing isothermal nucleic acid amplification tests : Towards democratization of diagnostics
Sammanfattning : Modern healthcare is the result of scientific advancement across disciplines and has enabled us to understand the rationale behind many diseases and how to treat or cure them; but still a myriad of unanswered questions remains. Especially infectious diseases play an important role in healthcare as they pose a constant threat for global health and well-being. LÄS MER