Sökning: "Lukas Gustafsson"

Hittade 3 avhandlingar innehållade orden Lukas Gustafsson.

  1. 1. Topics in projective algebraic optimization

    Författare :Lukas Gustafsson; Sandra Di Rocco; Kathlén Kohn; Cordian Riener; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : This thesis explores optimization challenges within algebraic statistics, employing both topological and geometrical methodologies to derive new insights. The main focus is the optimization degree of nearest point and Gaussian maximum likelihood estimation problems with algebraic constraints. LÄS MER

  3. 2. Pathway analysis: methods and perspectives

    Författare :Gustavo Stolf Jeuken; Lukas Käll; Mika Gustafsson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; pathway analysis; mutual information; survival analysis; enrichment analysis; transcriptomics.; Biotechnology; Bioteknologi;

    Sammanfattning : The amount of data being generated by high throughput molecular biology experiments grows every day, both in quantity and quality. With this comes the desire to have more powerful and comprehensive methods for statistical analysis that have been developed with the nature of this data in mind. LÄS MER

  4. 3. Network-based biomarker discovery for multiple sclerosis

    Författare :Julia Åkesson; Mika Gustafsson; Zelmina Lubovac-Pilav; Lukas Käll; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Complex autoimmune diseases, such as multiple sclerosis (MS), develop as a result of perturbations in the regulatory system controlling the function of immune cells. The disease course of MS is heterogeneous but is characterised by chronic inflammation in the central nervous system causing neurodegeneration resulting in gradual disability worsening. LÄS MER