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  1. 1. The Roles of Growth Factor Interactions and Mechanical Tension in Angiogenesis

    Författare :Ludvig Petersson; Pär Gerwins; Filip Farnebo; Uppsala universitet; []
    Nyckelord :angiogenesis; myofibroblast; wound healing; VEGF; FGF; PDGF; endocan; endothelial cell; vascularization; MEDICINE; MEDICIN; Medicin; Medicine;

    Sammanfattning : Angiogenesis, the formation of new blood vessels from preexisting ones through creation of new vessel branch points by sprouting or vessel splitting, is an important part of tissue growth in both physiological processes like wound healing and pathological conditions such as cancer. Growth factors like VEGF-A, FGF-2 and PDGF-BB are involved in both types of angiogenesis. LÄS MER