Sökning: "Kristofer Thörn"

Hittade 1 avhandling innehållade orden Kristofer Thörn.

  1. 1. Palmitate-induced Apoptosis in Insulin-producing β-cells

    Författare :Kristofer Thörn; Peter Bergsten; Claes Wollheim; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ER stress; apoptosis; palmitate; sphingosine-1-phosphate; ceramide; beta-cell; fatty acid; Medical cell biology; Medicinsk cellbiologi; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : Type 2 diabetes is a disease characterized by the inability of pancreatic β-cells to secrete sufficient amounts of insulin to maintain normoglycemia. Increased levels of saturated fatty acids such as palmitate are believed to contribute to β-cell failure and the development of the disease. LÄS MER