Sökning: "Claes Wollheim"

Hittade 2 avhandlingar innehållade orden Claes Wollheim.

1. 1. Complement receptor-mediated signal transduction in human neutrophils : A role for protein kinase C in the phagocytic process

   Författare :Maria Fällman; Claes B. Wollheim; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : The neutrophil granulocyte comprises the first line of human defense against invading microorganisms. A versatile motile machinery enables the cell to migrate to the inflammatory site and there engulf and destroy the pathogens by phagocytosis. LÄS MER

3. 2. Palmitate-induced Apoptosis in Insulin-producing β-cells

   Författare :Kristofer Thörn; Peter Bergsten; Claes Wollheim; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ER stress; apoptosis; palmitate; sphingosine-1-phosphate; ceramide; beta-cell; fatty acid; Medical cell biology; Medicinsk cellbiologi; Medical Cell Biology; Medicinsk cellbiologi;

   Sammanfattning : Type 2 diabetes is a disease characterized by the inability of pancreatic β-cells to secrete sufficient amounts of insulin to maintain normoglycemia. Increased levels of saturated fatty acids such as palmitate are believed to contribute to β-cell failure and the development of the disease. LÄS MER