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Visar resultat 1 - 5 av 21 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Prospective and longitudinal human studies of lead and cadmium exposure and the kidney

    Författare :Johan Nilsson Sommar; Ingvar A Bergdahl; Max Petzold; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cadmium; end-stage renal disease; kidney; lead; longitudinal; matched case-control; mixed effects; prospective; Occupational and Environmental Medicine; arbets- och miljömedicin;

    Sammanfattning : Cadmium and lead accumulate in humans and can have toxic effects. Exposure to cadmium is well known to cause kidney damage. Cadmium binds to metallothioneins, proteins that play a role in cadmium transport. LÄS MER

  3. 2. Urinary Clara cell protein and alpha 1-microglobulin – biomarkers of changes in kidney and airway function

    Författare :Lena Andersson; Göteborgs universitet; []
    Nyckelord :biomarker; Clara cell 16 kDa protein CC16 ; alpha 1-microglobulin A1M ; ambient air pollution; renal function; pyelonephritis; children;

    Sammanfattning : Validated biomarkers are useful tools for screening large populations. The benefit of screening may be improved risk assessment or early indications of adverse effects before detection or onset of symptoms. LÄS MER

  4. 3. Renal function decline and optimized planning for kidney replacement therapy

    Författare :Ulrika Hahn Lundström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic Kidney disease (CKD) is an increasing health problem world-wide, and the prevalence increases with age. CKD is a life-threatening condition, with high risk of cardiovascular disease and mortality. Patients with advanced CKD often need Kidney Replacement Therapy, (KRT), this includes transplantation, dialysis or conservative care. LÄS MER

  5. 4. Growth hormones in chronic kidney disease

    Författare :Erik Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Several hormonal systems are disrupted in chronic kidney disease (CKD) and disturbances of the growth hormone axis could contribute to increased morbidity and mortality through effects on cardiovascular health, energy metabolism and inflammation. The overall aim of this thesis was to increase knowledge about hormonal alterations and their consequences in CKD, focusing on cardiovascular disease (CVD), mortality and the growth hormone axis in end-stage renal disease. LÄS MER

  7. 5. Innovative approaches to study basophil function in inflammation

    Författare :Zenib Aljadi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Basophils are circulating granulocytes. They are very rare and represent less than 1% of peripheral blood leukocytes. Basophils connect the innate and adaptive immune responses by the secretion of a variety of immune-mediators involved in the pathogenesis of many inflammatory diseases mainly allergic reactions and autoimmune diseases. LÄS MER