Avancerad sökning

Hittade 3 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Synthesis of Organic Compounds for Nuclide Therapy : Derivatives of Carboranes, 9-Aminoacridine and Anthracyclines

   Författare :Senait Ghirmai; Stefan Sjöberg; Vladimir Tolmachev; Tor Kihlberg; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; 9-Aminoacridin; Carborane; Daunorubicin; Doxorubicin; BNCT; Iodine-125; Organisk kemi; Organic chemistry; Organisk kemi;

   Sammanfattning : This thesis addresses the synthesis of organic compounds, some of them are derivatives of compounds with DNA binding properties, for potential use in targeted nuclide therapy. The compounds synthesized therefore also need to contain potent nuclides. LÄS MER

3. 2. Aspects of dose, dose rate and radioisotopes in brachytherapy of uveal melanoma

   Författare :Maria Fili; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Uveal melanomas constitute melanomas arising from the choroid, the ciliary body or the iris, and in adults stands for the most common primary malignant intraocular tumor. It has a high risk of metastatic spread followed by inevitable death, and unfortunately the prognosis has not improved over the last decades. LÄS MER

4. 3. Development of radioligands for the serotonergic neurotransmission system for use in positron emission tomography

   Författare :Johan Sandell; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :PET; Radioligand; Brain; 5-HT1A receptor; serotonin transporter;

   Sammanfattning : The serotonergic system is implicated in several neuropsychiatric disorders, such as depression, anxiety and schizophrenia. Several hypotheses on the pathophysiology of these disorders are based on the pharmacology of serotonergic drugs. Selective serotonin reuptake inhibitors (SSRIs) are widely used for the treatment of depression and anxiety. LÄS MER