Sökning: "Gliogenesis"

Visar resultat 6 - 10 av 15 avhandlingar innehållade ordet Gliogenesis.

  1. 6. Signaling mechanisms underlying neural stem cell differentiation. Implications of BMPs, retinoids, and MAP kinases

    Författare :Roland Faigle; Göteborgs universitet; []
    Nyckelord :neural stem cells; differentiation; BMP; ASK1; p38 MAP kinase; CNTF; retinoic acid;

    Sammanfattning : Introduction: Neural stem cells are proliferating cells, derived from the nervous system with the ability to give rise to neurons, astrocytes, and oligodendrocytes. The molecular events and signaling pathways regulating neural stem cell differentiation are largely unknown. LÄS MER

  3. 7. Let's talk about SOX : diverse key players in the transcriptional regulation of neural stem cells

    Författare :Susanne Klum; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The development of the central nervous system relies on neural stem cells. How these stem cells either maintain their identity as self-renewing progenitors or differentiate into cells of the neuronal or glial lineage are fundamental questions. LÄS MER

  4. 8. Neurogenesis, neural stem cells and nitric oxide in neuroinflammation

    Författare :Alexandre I Danilov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neurogenesis; neuronal stem cells; nitric oxide; Multiple Sclerosis; EAE; brain trauma;

    Sammanfattning : We investigated whether nitric oxide (NO) is produced in MS patients, determining the concentrations of its oxidation products (NOx) in CSF. The total levels of NOx in CSF were significantly increased in all MS groups as compared to healthy controls and tension headache patients. LÄS MER

  5. 9. Regenerating the brain : stem cell differentiation and cholinergic dysfunction in Alzheimer disease

    Författare :Linn Malmsten; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hippocampal neurogenesis in the adult brain is important for learning and memory processes, which are heavily affected in Alzheimer disease (AD). Thus, targeting processes that could stimulate neurogenesis is a logical step in the search for strategies offering neuronal renewal and brain repair. LÄS MER

  7. 10. The Role of miRNA in Neurogenesis and Cell Specification

    Författare :Malin Åkerblom; Molekylär neurogenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; miRNA; microRNA; miR-124; miR-9; miR-125; adult neurogenesis; neural stem cells; cell specification; microglia; lentiviral vectors; olfactory bulb; olfactory bulb interneurons;

    Sammanfattning : Only a few decades ago, it was generally believed that gene expression was controlled in a unidirectional way, i.e. DNA was transcribed into RNA, which simply acted as a messenger molecule used to produce the protein that executed cellular functions. LÄS MER