Sökning: "D1 receptor"

Visar resultat 21 - 25 av 98 avhandlingar innehållade orden D1 receptor.

  1. 21. Involvement of lipid rafts in G protein-coupled monoamine receptor trafficking and signaling : a pharmacological approach

    Författare :Benita Sjögren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The present work focused on lipid raft-mediated modulation of signaling and trafficking of serotonin (5-HT) and dopamine receptors. The 5-HT system is one of the most complex neurotransmitter systems, with a wide distribution both in the CNS and in the periphery. LÄS MER

  3. 22. A PET study on dopamine and serotonin receptor binding in the primate brain : challenges with antipsychotic drugs and amphetamine

    Författare :Yuan-Hwa Chou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The brain imaging technique positron emission tomography (PET) has been applied to study dopamine and serotonin neurotransmission. In schizophrenia research, an important observation is that patients with schizophrenia, when compared with controls, have higher amphetamine induced dopamine release in the striatum. LÄS MER

  4. 23. The functional role of the lateral olivocochlear system and mechanisms underlying sound condtioning

    Författare :Xianzhi Niu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cochlea; dopamine; tyrosine hydroxylase; sound conditioning; apoptosis; acoustic trauma; lateral olivocochlear nucleus; D1 receptor; efferents;

    Sammanfattning : Sound conditioning is a process induced by a low-level, non-damaging acoustic stimulus that provides protection against subsequent detrimental forms of acoustic trauma. Many hypotheses have been advanced to explain the effect of sound conditioning, but the mechanisms underlying this phenomenon are still not yet known. LÄS MER

  5. 24. Dopamine coordinates the effect of natriuretic and antinatriuretic factors

    Författare :Susanne Crambert; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Living organisms are dependent on a precise regulation of water and sodium. The stability of the internal environment is maintained through a series of feedback mechanisms, in response to changes within the organism as well as to changes in the external environment. LÄS MER

  7. 25. Up-regulation of dopamine D₂ receptors : in vitro and in vivo studies

    Författare :Maria Wanderoy; Eliassitet Eriksson; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurochemistry; Neurokemi; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Sammanfattning : In the central nervous system (CNS) dopaminergic and dopaminoceptive neurons have the ability to respond to variations in dopamine levels by for example adjusting their dopamine receptor levels. One of the most well known phenomena in this respect is that long-term blockade of D2 receptors with antipsychotic drugs leads to an increase in striatal D2 receptor density of experimental animals as well as of schizophrenic patients as measured in both post-mortem studies and in vivo positron emission tomography studies of brain. LÄS MER