Sökning: "ESTs"

Visar resultat 1 - 5 av 20 avhandlingar innehållade ordet ESTs.

  1. 1. Patentability of nucleic acid related inventions in Europe and in the USA

    Författare :Kristina Runeberg; [2001]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; patentability; expressed sequence tags; United States Patent and Trademark Office; European Patent Office; EPO; nucleic acid; USPTO; ESTs; patent; DNA;

    Sammanfattning : .... LÄS MER

  2. 2. Development of New Methods for Inferring and Evaluating Phylogenetic Trees

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Tobias Hill; Uppsala universitet.; [2007]
    Nyckelord :Pharmacology; Evolution; Phylogeny; SPR; Genetic Algorithm; Tree metrics; Farmakologi;

    Sammanfattning : Inferring phylogeny is a difficult computational problem. Heuristics are necessary to minimize the time spent evaluating non optimal trees. In paper I, we developed an approach for heuristic searching, using a genetic algorithm. Genetic algorithms mimic the natural selections ability to solve complex problems. LÄS MER

  3. 3. Gene finding in Populus- The Bioinformatics of a EST program

    Detta är en avhandling från Stockholm : Bioteknologi

    Författare :Rupali Bhalerao; [2003]
    Nyckelord :;

    Sammanfattning : During the course of the work described in this thesis, ESTsequencing project was initiated in woody plant poplar forlarge scale gene discovery in a tree specie. Since most of thetree genomes are considerably large in size, EST sequencing wasconsidered to be a cost effective method for gene discovery. LÄS MER

  4. 4. A Genetic Survey of the Pathogenic Parasite Trypanosoma cruzi

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Anh-Nhi Tran; Lena Åslund; John Kelly; [2003]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Trypanosoma cruzi; Chagas ; gene discovery; EST; sequencing; DGC3; repeats; gene family; CL Brener; trypanothione synthetase; TcTRS locus; alleles; polymorphism; RNA-binding protein; TcPTB; stage-specific expression; Genetik; NATURAL SCIENCES Biology Cell and molecular biology Genetics; NATURVETENSKAP Biologi Cell- och molekylärbiologi Genetik; medicinsk genetik; Medical Genetics;

    Sammanfattning : Trypanosoma cruzi, the causative agent of Chagas´ disease, is an evolutionarily ancient species with distinct biological and immunological characteristics. A fundamental understanding of the basic biology of the parasite is necessary in order to develop reliable therapeutic and prophylactic agents against T. cruzi. We have, as a part of the T. LÄS MER

  5. 5. Molecular Characterization of Genomic Amplifications in Pancreatic Cancer

    Detta är en avhandling från Markus Heidenblad, Department of Clinical Genetics, Lund University Hospital, SE-221 85 LUND, Sweden

    Författare :Markus Heidenblad; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FISH; Clinical genetics; PCR; cDNA microarray; array-based CGH; expression profiling; genomic profiling; Pancreatic cancer; gene amplification; Klinisk genetik;

    Sammanfattning : Pancreatic cancer includes multiple histologic subtypes that show large differences in their clinical and biological characteristics. Despite this diversity, more than 85% of the neoplasms in the organ are malignant ductal adenocarcinomas, which are the focus of the present thesis. LÄS MER