Sökning: "ESTs"

Visar resultat 1 - 5 av 21 avhandlingar innehållade ordet ESTs.

  1. 1. Patentability of nucleic acid related inventions in Europe and in the USA

    Författare :Kristina Runeberg; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; patentability; expressed sequence tags; United States Patent and Trademark Office; European Patent Office; EPO; nucleic acid; USPTO; ESTs; patent; DNA;

    Sammanfattning : .... LÄS MER

  3. 2. Development of New Methods for Inferring and Evaluating Phylogenetic Trees

    Författare :Tobias Hill; Helgi Schiöth; Robert Fredriksson; Mark Wilkinson; Uppsala universitet; []
    Nyckelord :Pharmacology; Evolution; Phylogeny; SPR; Genetic Algorithm; Tree metrics; Farmakologi;

    Sammanfattning : Inferring phylogeny is a difficult computational problem. Heuristics are necessary to minimize the time spent evaluating non optimal trees. In paper I, we developed an approach for heuristic searching, using a genetic algorithm. Genetic algorithms mimic the natural selections ability to solve complex problems. LÄS MER

  4. 3. A Genetic Survey of the Pathogenic Parasite Trypanosoma cruzi

    Författare :Anh-Nhi Tran; Lena Åslund; John Kelly; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Trypanosoma cruzi; Chagas ; gene discovery; EST; sequencing; DGC3; repeats; gene family; CL Brener; trypanothione synthetase; TcTRS locus; alleles; polymorphism; RNA-binding protein; TcPTB; stage-specific expression; Genetik; Genetics; Genetik; medicinsk genetik; Medical Genetics;

    Sammanfattning : Trypanosoma cruzi, the causative agent of Chagas´ disease, is an evolutionarily ancient species with distinct biological and immunological characteristics. A fundamental understanding of the basic biology of the parasite is necessary in order to develop reliable therapeutic and prophylactic agents against T. cruzi. We have, as a part of the T. LÄS MER

  5. 4. Gene finding in Populus- The Bioinformatics of a EST program

    Författare :Rupali Bhalerao; KTH; []
    Nyckelord :;

    Sammanfattning : During the course of the work described in this thesis, ESTsequencing project was initiated in woody plant poplar forlarge scale gene discovery in a tree specie. Since most of thetree genomes are considerably large in size, EST sequencing wasconsidered to be a cost effective method for gene discovery. LÄS MER

  7. 5. Molecular Characterization of Genomic Amplifications in Pancreatic Cancer

    Författare :Markus Heidenblad; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FISH; Clinical genetics; PCR; cDNA microarray; array-based CGH; expression profiling; genomic profiling; Pancreatic cancer; gene amplification; Klinisk genetik;

    Sammanfattning : Pancreatic cancer includes multiple histologic subtypes that show large differences in their clinical and biological characteristics. Despite this diversity, more than 85% of the neoplasms in the organ are malignant ductal adenocarcinomas, which are the focus of the present thesis. LÄS MER