Avancerad sökning

Hittade 4 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Regulation of T-cell proliferation and B-CLL apoptosis by CD6 and FAS/FASL

    Författare :Lydia Maria Osorio Fernández; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :T-cell activation; CD6; B-CLL; apoptosis; Fas; FasL;

    Sammanfattning : T-cell activation involves the interaction between the T-cell receptor (TCR) and the peptide/MHC complex presented on an antigen-presenting cell. However, this is not sufficient for the full development of T cell responses and co-stimulatory signals from accessory molecules are required. LÄS MER

  2. 2. Patterns in big data bioinformatics : Understanding complex diseases with interpretable machine learning

    Författare :Mateusz Garbulowski; Jan Komorowski; Ryan J. Urbanowicz; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; complex diseases; big data; machine learning; transcriptomics; life sciences; rough sets; Bioinformatics; Bioinformatik;

    Sammanfattning : Alterations in the flow of genetic information may lead to complex diseases. Such changes are measured with various omics techniques that usually produce the so-called “big data”. Using interpretable machine learning (ML), we retrieved patterns from transcriptomics data sets. LÄS MER

  3. 3. Periodontal medicine : oral inflammatory conditions with special emphasis on immunological aspects

    Författare :Jeneen Panezai; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Systemic effects of periodontal disease have been a subject of interest for the past century, with intense focus converging since the past decade. Both rheumatoid arthritis (RA) and periodontal disease (PD) are immuno-inflammatory diseases with osteolysis as its hallmark feature. Activated T cells are known to modulate osteoclastogenesis. LÄS MER

  4. 4. Compassionate mind training and its relationship with perceived stress, poor mental health, self-compassion and benevolence

    Författare :Christina Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: University students and employees are two populations where stress-related problems, anxiety, and depression are increasing. Interventions must be found to reverse this trajectory and to improve mental health. LÄS MER