Sökning: "CD4 CD8 ratio"

Visar resultat 11 - 15 av 30 avhandlingar innehållade orden CD4 CD8 ratio.

1. 11. Airway inflammation in "healthy" smokers. Relation to lung function and high resolution CT findings

   Författare :Ann Ekberg-Jansson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic obstructive pulmonary disease; smoking; bronchoalveolar lavage; bronchial biopsies; cytokines; lymphocytes; computed tomography; lung function; respiratory symptoms;

   Sammanfattning : The aim of the present study was to characterize the inflammatory pattern in "healthy"smokers and relate it to lung function, high resolution computed tomography (HRCT) findings and respiratory symptoms in order to identify smokers at risk to develop COPD. Subjects were recruited from a population study "Men born 1933 in Göteborg". LÄS MER

3. 12. Cancer associated fibroblasts and T cells in pancreatic cancer : an immune perspective

   Författare :Laia Gorchs; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : About 90% of pancreatic cancers are pancreatic ductal adenocarcinomas (PDAC) and its deadly hallmarks, including a prominent fibrotic stroma, low mutational burden, lack of early diagnosis and rapid metastasis, contribute to trial failures and to the poor five-year overall survival rate of only 9%. Carcinoma associated fibroblasts (CAFs) are the most abundant cell type in the stroma of PDAC and their interactions with tumor cells leading to tumor progression have been extensively studied. LÄS MER

4. 13. Leishmania and HIV-1 interaction : immunopathogenic mechanisms

   Författare :Dawit Wolday; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Both Leishmania and HIV can infect and multiply in macrophages, and both can dysregulate the T-helper (Th) immune system. This thesis was, therefore, undertaken to unravel some of the underlying immunopathogenic mechanisms of the interaction of the two pathogens. LÄS MER

5. 14. From youth to adult : studies on chronic airway obstruction with special reference to events in the neonatal period

   Författare :Petra Um-Bergström; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Introduction: In western countries, 6-12% of all pregnancies end preterm, i.e. before 37 weeks of gestation. After the introduction of antenatal corticosteroids and improvements of neonatal intensive care, survival rates for children born preterm have increased worldwide. LÄS MER

7. 15. Experimental modulation and suppression of anti-allograft immune response

   Författare :Öyvind Östraat; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; linomide; leflunomide; cyclophosphamide; mycophenolate mofetil; azathioprine; thalidomide; cyclosporin A; ciprofloxacin; flow cytometry; production; IL-2; Rat cardiac transplantation; allograft; Immunology; serology; transplantation; Immunologi; serologi;

   Sammanfattning : Abstract The objective of this investigation was to characterise the immunomodulatory or immunosuppressive effects of single drug treatment and the potential synergistic or additive effects of combined treatment with the focus on ciprofloxacin, thalidomide, mycophenolate mofetil, azathioprine, cyclophosphamide or leflunomide added to cyclosporin A (CyA). A rat cardiac transplant model was used to study graft survival and the influence on lymphocytes was evaluated by in vitro tests. LÄS MER