Sökning: "Basic Medicine Physiology"

Visar resultat 26 - 30 av 341 avhandlingar innehållade orden Basic Medicine Physiology.

  1. 26. Immunopathogenesis of schistosomiasis mansoni : Immunity and pathology in a primary and a secondary infection following chemotherapy in the mouse and the baboo models

    Författare :Idle Omar Farah; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; Baboon; BALB c mice; Chemotherapy; Cytokines; Fibrosis; Granuloma; Modulation; Pathology; Reinfection; Schistosoma mansoni; Th1; Th2; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Medicine; medicin;

    Sammanfattning : This thesis describes a series of experiments aimed at elucidating the mechanisms ofimmunity and pathology elicited by both a primary infection and a reinfection exposure toSchistosoma mansoni following chemotherapy. The effects of a single large cercarial doseand a cumulatively equivalent dose, administered as multiple small doses are compared. LÄS MER

  3. 27. Development and validation of a localized murine candidiasis model : The pathogenesis, chemotheraphy and defense mechanisms to Candida mastitis in the lactating mouse

    Författare :Faisal Abdi Guhad; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; Murine model; Candida albicans; Pathogenesis; Virulence factors; Amphotericin B; Fluconazole; Complement activation; C3c; SCID mice; Nude mice; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Sammanfattning : A murine model of localized candidiasis (mastitis) was developed. The model was analyzed withrespect to its discriminative abilities through investigation of the virulence properties of C.albicans mutant strains compared with the wild-type parental strain. LÄS MER

  4. 28. Studies of nucleotide receptors-induced calcium response in glomerular mesangial cells and afferent arterioles

    Författare :Antonio M. Gutiérrez; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; mesangial cells; nucleotide receptors; purinoceptors; desensitization; afferent arterioles; ATP; UTP; adenosine; protein phosphatases; calcium; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Sammanfattning : It is known that intracellular calcium concentration ([Ca2+]i) changes in rat glomerular mesangial cells (GMC) and rabbit afferent arterioles (AA) in response to extracellular nucleotides. We studied the nucleotide-induced calcium response in cultured GMC and AA. LÄS MER

  5. 29. Echocardiographic measurements of the heart : with focus on the right ventricle

    Författare :Karin Loiske; Kent Emilsson; Allan Sirsjö; Jan Engvall; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Echocardiography; heart; right ventricle; right ventricular outflow tract 1; isovolumetric relaxation time; maximal early diastolic relaxation velocity; takotsubo cardiomyopathy; long-axis function; MEDICINE; MEDICIN; Clinical physiology; Klinisk fysiologi; Biomedicin; Biomedicine;

    Sammanfattning : Echocardiography is a well established technique when evaluating the size and function of the heart. One of the most common ways to measure the size of the right ventricle (RV) is to measure the RV outflow tract 1(RVOT1). Several ways to measure RVOT1 are described in the literature. LÄS MER

  7. 30. Alpha-2 Adrenergic Receptors and Signal Transduction : Effector Output in Relation to G-Protein Coupling and Signalling Cross-Talk

    Författare :Johnny Näsman; Peter Evans; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; Adrenergic; receptor; G-protein; adenylyl cyclase; cAMP; calcium; cross-talk; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Sammanfattning : The alpha-2 adrenergic receptor (α2-AR) subfamily includes three different subtypes, α2A-, α2B- and α2C-AR, all believed to exert their function through heterotrimeric Gi/o-proteins. The present study was undertaken in order to investigate subtype differences in terms of cellular response and to explore other potential signalling pathways of α2-ARs. LÄS MER